DISCLOSURES: NONE ABSTRACT Background: Sickle cell anaemia is a multi-systemic disease with variable clinical manifestations including those involving the digestive system. There is paucity of data on the digestive system complications of sickle cell anaemia in children in our setting. Objective: To determine the pattern of digestive system complications among hospitalized children with sickle ...

background: gastrointestinal and liver diseases (gild) constitute a noteworthy portion of causes of death and disability in iran. however, data on their prevalence and burden is sparse in iran. the global burden of disease (gbd) study in 2010 has provided invaluable comprehensive data on the burden of gild in iran methods: estimations of death, years of life lost due to premature death (yll), y...

BACKGROUND PD-L1 has been reported to be expressed in diverse human malignancies. However, the prognostic value of PD-L1 in digestive system cancers remains inconclusive. Therefore, we conducted this meta-analysis to evaluate the prognostic impact of PD-L1 expression in digestive system cancers. MATERIALS AND METHODS We searched the PubMed, Embase, and the Chinese National Knowledge Infrastru...

The prognostic nutritional index (PNI) has been reported to correlate with the prognosis in patients with various malignancies. We performed a meta-analysis to determine the predictive potential of PNI in digestive system cancers. Twenty-three studies with a total of 7,384 patients suffering from digestive system carcinomas were involved in this meta-analysis. A lower PNI was significantly asso...

UNLABELLED AIR-FILLED CYSTS: Pneumatosis cystoides intestinalis (PCI) is a benign air-filled cystic formation lying in submucosal or subserous digestive tissue. PCI has been reported all along the digestive tract. CLINICAL SIGNS Manifestations of PCI vary greatly. Some cases are asymptomatic, while others are revealed by abdominal pain or pneumoperitoneum. Outcome is usually favorable. EXPL...

Bacterial endocarditis is the infection of inner lining of heart and /or heart valves. This disease is usually related to the presence of some pathogenic bacteria in mouth, digestive system or urinary tract. Most of the times, this infection happens in people with heart problems like the presence of prosthetic valves, history of previous endocarditis, some congenital heart defects and heart tra...

In Ayurvedic system of medicine, Agni maximally represents digestive & metabolic fire in the body. It is the substance in the secretions of the body which are directly responsible for digestive and chemical changes in the body. Ingested food is to be digested, absorbed and assimilated, which is unavoidable for the maintenance of life, and is performed by the Agni. According to the functions and...

No treatment has been proven to be effective in nonalcoholic fatty liver disease (NAFLD) and/or steatohepatitis (NASH). Numerous studies have addressed this issue. However conclusive recommendations cannot be drawn solely from the currently available studies. Hence we performed this systematic review to determine which of the available therapeutic modalities are supported by adequate evidence i...

Gastrointestinal disease is a prevalent cause of morbidity and mortality and the use of animal models have been instrumental in studying mechanisms of digestive pathophysiology. As investigators attempt to translate the wealth of basic science information developed from rodent, models, large animal models provide a number of translational advantages. The pig, in particular, is arguably one of t...

Every May 29th the World Gastroenterology Organization (WGO) celebrates World Digestive Health Day (WDHD) and initiates a worldwide public health campaign through its 110 national societies and 50,000 members. Each year focuses on a particular digestive disorder in order to increase general public awareness of prevention and therapy. 2010 is dedicated to inflammatory bowel disease (IBD). Upon t...