Herein we report an investigation of the efficacy of pyridine and pyrimidine analogs of acetaminophen (ApAP) as peroxyl radical-trapping antioxidants and inhibitors of enzyme-catalyzed lipid peroxidation by cyclooxygenases (COX) and lipoxygenases (LOX). In inhibited autoxidations we find that ApAP, the common analgesic and antipyretic agent, is a very good antioxidant with a rate constant for r...

selective transformation of 2-propargylthio-6-methyl-pyrimidin-4(1h)on e (2) to 3,5-dimethyl-7h-thiazolo [3,2-a] pyrimidin-7-one (3) is performed under the conditionof base catalysis . for elucidation of structure, palladium catalyzed cyclization reaction of (2) was carried out and the structures of the products were assigned (5) and (6). these compounds underwent isomerization to (3) and (4) r...

Abstract The synthesis, characterization and catalytic activity of copper(II)‐ bis (imino)pyridine pincer complexes were described. copper(II) ( 2 a b ) synthesized by the reaction 2,6‐ ligands with CuCl ⋅ 2H O in methanol as solvent. fully characterized IR, UV‐Visible, Mass spectroscopy elemental analysis. showed excellent towards azide‐alkyne cycloaddition (Click reaction) water produced regi...

Mahmoud Zarei was born in Hamedan, Iran in1986. He received his B.Sc. in Pure Chemistry (2010) from Islamic Azad University Arak and M.Sc. in Organic Chemistry (2013) at Bu-Ali Sina University, Iran. He is currently working towards his Ph.D. under the supervision of Professor Mohammad Ali Zolfigol. His research interest is catalysis, including the application of homogeneous and heterogeneous ca...

Group VIII B metal oxides supported on gamma-alumina were investigated as catalysts and promoters of MoO3 hydrodesulfurization catalysis. Superior promotion was observed in PbO promoted catalyst compared to that of CoO, the typically accepted promoter. Other metal oxides, SnO and Ho2O3 exhibited reasonable hydrodesulfurization catalysis promotion but lower than for CoO promoted catalyst.

Abstract: Systematic studies on the substituent effect in para substituted Fe(CO)4–pyridine complexes have been studied on the basis of DFT quantum-chemical calculations. The following substituents were taken into consideration: NO2, CN, CHO, F, H, CH3, and OH. Additionally, the Fe–N and Fe–C bonds were characterized on the basis of Atoms in Molecules topological analysis of electron density. I...

First, Schiff base iminopyridine ligands has been prepared by the condensation between primaryamines, different substituted anilines and active carbonyl group of pyridine carboxaldehyde, thenthe complexes [diiodo (3-ethylphenyl) pyridine-2-yl methylene amine] mercury(II), complex a,[dibromo (2,5-dimethylphenyl) pyridine-2-yl methylene amine] mercury(II) complex b, and[dinitrato bis-(2,6-dimethy...

nicotine-based ionic liquid has been used as a green catalyst for pyridine-catalyzed huisgen reaction. it promoted addition of dimethylacetylenedicarboxylate to aldehydes or n-tosyl imines leading to efficient synthesis of 2-benzoylfumarates and 1-azadienes respectively under pyridine free odorless ionic liquid conditions. the improved results were obtained in terms of enhanced yields, with min...