The non-functional QoS (quality of service) information helps us to select a proper Web-service from the web applications, by using component services such as UDDI[1](Universal Description, Discovery, and Integration) and MDS(Monitoring and Discovery System). MDS is a suite of web services to monitor and discover resources and service on Grids, but MDS only based on function aspects. This paper...

There are 2 excellent reasons to compute usability problem-discovery rates. First, an estimate of the problem-discovery rate is a key component for projecting the required sample size for a usability study. Second, practitioners can use this estimate to calculate the proportion of discovered problems for a given sample size. Unfortunately, smallsample estimates of the problem-discovery rate suf...

Early recognition of potential QT/TdP liability is now an essential component of the drug discovery/drug development program. The hERG assay is an indispensable step and a high-quality assay must accompany any investigational new drug (IND) application. While it is the gold standard at present, the hERG assay is too labor-intensive and too low throughput to be used as a screen early in the disc...

When data is maintained over geographically distributed sites the computational power of distributed and parallel systems can be exploited for knowledge discovery in scientific data. In this scenario the Grid can provide an effective computational support for distributed knowledge discovery on large datasets. In particular, Grid services for data integration and analysis can represent a primary...

Compound acquisition has always been a very important component in the discovery and development of new biologically active entities. With the rapid advances in high throughput screening coupled with the ever-decreasing time requirements for the discovery phase, the number and quality of compounds screened is of great importance. This presentation will discuss some of the techniques and process...

D etailed note-keeping is a prerequisite for, if not a key component of, scientific discovery. An unrecorded experiment is lost to the world even if it sparks a great idea in a scientist’s mind: Additional work is needed to reproduce and confirm the original observation and to test the hypothesis by novel experimental strategies. Hence, a detailed record of the experimental setup, observations,...

Mobile semantic grids are characterized by high heterogeneity and volatility of their component nodes. Hence, discovery procedures more flexible than the ones borrowed from wired approaches are desirable. We present a hybrid ZigBee/Bluetooth grid infrastructure where Knowledge Representation techniques and technologies have been exploited to perform a capillary data dissemination, to interconne...

Service advertisement and discovery is an important component for mobile ad hoc communications and collaboration in ubiquitous computing environments. The ability to discover services offered in a mobile ad hoc network is the major prerequisite for effective usability of these networks. This paper aims to classify and compare existing Service Discovery (SD) protocols for MANETs by grouping them...

This paper stresses the contribution of the process of knowledge discovery in databases for the effective creation and sharing of organizational knowledge. The focus on the process of knowledge discovery has been mainly technological. The paper attempts to enrich that perspective by stressing the insights gained by integrating the knowledge discovery process in the social process of knowledge c...