abstract objective the last two decades have seen major advancements in our understanding of some of the most common neurodevelopmental disorders in the field of child neurology. however, in the majority of individual patients, it is still not possible to arrive at a molecular diagnosis, due in part to lack of knowledge of molecular causes of these tremendously complex conditions. common geneti...

Disease prevalence mapping allows countries to identify infected individuals and populations in need of diseasecontrol measures, such as mass drug administration (MDA) with preventive chemotherapy. For countries with unlimited time and resources, diseasespecific prevalence mapping may be carried out in a slow, careful manner, by large teams of diagnostic technicians, supervisors, and drivers. T...

g20 world brain mapping initiative (neuroscience/n-20) is putting brain mapping on the top of global economic issues the society for brain mapping, therapeutics, and brain mapping foundation are propelling therapeutic advances in nano-neurosurgery, nano-bio-electronics, artificial intelligence, neuro-supercomputing and ‘cross-pollination’ among the bio-medical sciences and engineering worldwide...

the focus of this study is to analyze the text world of omar khayyam's poetry by a novel approach called cognitive poetics. to examine the author’s/reader's text world, the study has employed freeman’s model (1998). she believes that conceptual mapping in literary texts can operate at three different levels including “attribute mapping,” “relational mapping,” and “system mapping.” through readi...

Admixture mapping is a disease-mapping strategy to identify disease susceptibility variants in an admixed population that is a result of mating between 2 historically separated populations differing in allele frequencies and disease prevalence. With the increasing availability of high-density genotyping data generated in genome-wide association studies, it is of interest to investigate how to a...

Epigenomes are comprised, in part, of all genome-wide chromatin modifications, including DNA methylation and histone modifications. Unlike the genome, epigenomes are dynamic during development and differentiation to establish and maintain cell type-specific gene expression states that underlie cellular identity and function. Chromatin modifications are particularly labile, providing a mechanism...