BACKGROUND Fullerene compounds are known to possess antioxidant properties, a common property of chemical radioprotectors. DF-1 is a dendrofullerene nanoparticle with antioxidant properties previously found to be radioprotective in a zebrafish model. The purpose of this study was to evaluate the radioprotective effects of DF-1 in a murine model of lethal total body irradiation and to assess for...

background: in many studies, chemicals and natural materials were tested to reduce the harmful effects of radiation. it is known that famotidine and vitamin c reduce dna damage. objective: the aim of this study was to evaluate the radioprotective effect of vitamin c, cimetidine and famotidine on gamma-radiation-induced damage on mouse bone marrow.  methods: six-to-seven week male nmri mice (28 ...

Hibernation is a state of reduced metabolic activity used by some animals to survive in harsh environmental conditions. The idea of exploiting hibernation for space exploration has been proposed many years ago, but in recent years it is becoming more realistic, thanks to the introduction of specific methods to induce hibernation-like conditions (synthetic torpor) in non-hibernating animals. In ...

BACKGROUND AND PURPOSE The lens of the eye is sensitive to radiation. Children undergoing CT of the head and patients undergoing repeated CT scanning of the head are vulnerable to this complication. The purpose of this study was to test the ability of a heavy metal, bismuth, in reducing radiation to the lens of the eye during routine cranial CT. METHODS Both phantom and human studies were don...

BACKGROUND Hippophae rhamnoides, a high altitude habitat plant, has been extremely used in traditional medicinal practices for treating a variety of ailments. Recently, an extract (RH-3) prepared from berries of Hippophae rhamnoides has been reported to exhibit significant radioprotection against whole body lethal irradiation. OBJECTIVE Present study was undertaken to elucidate the DNA bindin...