The work undertaken involves the use of functional magnetic resonance imaging (fMRI) and magnetoencephalography (MEG) as separate but complementary non-invasive functional brain imaging modalities. The aim in combining fMRI and MEG is centred around exploitation of the high temporal resolution available in MEG, and the high spatial resolution available in fMRI. However, whilst MEG represents a ...

A sensitive method for the detection of age-related changes Magnetoencephalography (MEG) is a novel, state-of-the-art technique used in clinical neurophysiology, which promises better understanding of brain (dys)function. The " whole-head " MEG sensor-array enables a noninvasive visualization of the intracellular currents involved in transmission and processing of information in the working bra...

We have a limited understanding of why many children with attention deficit hyperactivity disorder do not outgrow the disorder by adulthood. Around 20-30% retain the full syndrome as young adults, and about 50% show partial, rather than complete, remission. Here, to delineate the neurobiology of this variable outcome, we ask if the persistence of childhood symptoms into adulthood impacts on the...

With sufficiently fast data sampling, ubiquitous sharp transients appear in magnetoencephalography (MEG) data. Initially, no known collective neuronal activity could explain MEG signal generation well above 100 Hz, so it was assumed that these transients were entirely composed of background electronic noise that could be eliminated by filtering and averaging. Recent studies at the cellular leve...

PURPOSE Ictal magenetoencephalographic (MEG) discharges convey significant information about ictal onset and propagation, but there is no established method for analyzing ictal MEG. This study sought to clarify the usefulness of time-frequency analyses using short-time Fourier transform (STFT) for ictal onset and propagation of ictal MEG activity in patients with neocortical epilepsy. METHODS...

This paper provides an overview on the basic principle and applications of magnetoencephalography, which requires the use of many SQUID channels and thus represents one of the more important application of superconducting electronic devices. This paper is divided into 8 sections. Section 1 is an overview of the MEG technique. Section 2 provides a short historical background on the method. Secti...

We present the design of a low-cost system for recording galvanic skin conductance responses (SCRs) from humans in a magnetically shielded room (MSR) simultaneously to magnetoencephalography (MEG). Such a system was so far not available to the MEG community. Its availability is of utmost importance for neuroscience, since it will allow the concurrent assessment of the autonomic and central nerv...

OBJECT In this study the authors evaluated the sensitivity and selectivity of a noninvasive language mapping procedure based on magnetoencephalography (MEG), for determining hemispheric dominance for language functions. METHODS Magnetic activation profiles of the brain were obtained from 100 surgical candidates (age range 8-56 years) with medically intractable seizure disorder by using a whol...

Objectives: A problem with the topographic mapping of MEG data recorded with axial gradiometers is that ®eld extrema are measured at sensors located at either side of a neuronal generator instead of at sensors directly above the source. This is problematic for the computation of event-related desynchronization (ERD) on MEG data, since ERD relies on a correspondence between the signal maximum an...