Extensive departures from balanced gene dose in aneuploids are highly deleterious. However, we know very little about the relationship between gene copy number and expression in aneuploid cells. We determined copy number and transcript abundance (expression) genome-wide in Drosophila S2 cells by DNA-Seq and RNA-Seq. We found that S2 cells are aneuploid for >43 Mb of the genome, primarily in the...

Background: A study has been conducted to assess two useful radiation protection indices, the annual per-capita effective dose equivalent (AED) and the genetically significant dose (GSD), from conventional diagnostic radiography in 10 counties with more than 1,886,000 inhabitants in Khorasan province in Iran. Materials and Methods: The health centre authorities of Khorasan province were asked t...

introduction radiation exposures from diagnostic medical examinations are generally low and are almost always justified by the benefits of accurate diagnosis of possible disease conditions. therefore, entrance skin dose (esd), body organ dose (bod), and effective dose (ed) from adult patients undergoing routine thorax posterior-anterior (pa) and thorax right lateral (rlat) were estimated in uni...

Introduction: To enhance the dose to tumor, the use of high atomic number elements has been proposed. Objective: The aim of this study is to investigate the effect of gold nanoparticle distribution on dose enhancement in tumor when the tumor is irradiated by typical monoenergetic X-ray beams by considering homogeneous and inhomogeneous distributions of gold nanoparticles (GNPs)...

Background: An effective method for management of large and bulky malignant tumors. This treatment modality is also known as Specially Fractionated Radiation Therapy (SFRT). In this treatment technique a grid block converted the open radiation field into a series of pencil beams. Dosimetric characteristics of an external beam grid radiation field have been investigated using experimental and Mo...

Herbicide resistance in little seed canary grass (Phalaris minor Retz.) wheat is the major sustainability issue, which puts rice-wheat (R-W) system north-western Indo-Gangetic Plains (IGP) under serious threat. To assess level, a questionnaires based survey with systematic approach was conducted during rabi 2017-18 five districts (Yamuna Nagar, Kaithal, Karnal, Fatehabad and Rohtak) of Haryana....

Background: Radiation dose knowledge through Xray examinations and their distribution in Iran provides useful guidance on patient dose reduction. The results of the entrance skin dose (ESDs) of five common radiographies in all radiology centers in Yazd province were reported in our previous study (2003). In the present study we have evaluated the collective effective dose of convention...

Background: To enhance the dose to tumor, the use of high atomic number elements has been proposed.Objective: The aim of this study is to investigate the effect of gold nanoparticle distribution on dose enhancement in tumor when the tumor is irradiated by typical monoenergetic X-ray beams by considering homogeneous and inhomogeneous distributions of gold nanoparticles (GNPs) in the tumor.Method...

Introduction: Regular implementation of quality control (QC) program in diagnostic X-ray facilities may affect both image quality and patient radiation dose due to the changes in exposure parameters. Therefore, this study aimed to investigate the status of randomly selected conventional radiographic X-ray devices installed in radiology centers of Great Khorasan Province, Iran, to produce the da...