BACKGROUND Cystic fibrosis (CF) is an inherited condition characterised by the abnormal transport of chloride ions across transporting epithelia. This leads to the production of thick sticky mucus in the lungs, pancreas, liver, intestine and reproductive tract, and an increase in the salt content in sweat. Among other problems, people with CF experience recurrent respiratory infections and have...

Neuropathic pain is common in peripheral nerve injury and often fails to respond to ordinary medication. Here, we investigated whether the two novel epigallocatechin-3-gallate (EGCG) polyphenolic derivatives, compound 23 and 30, reduce the neuropathic pain in mice chronic constriction nerve injury (CCI). First, we performed a dose-response study to evaluate nociceptive sensation after administr...

Background: Silicon (Si) can directly or indirectly enhance plant resistance to fungal pathogens, but no report is available concerning the effectiveness of Si in decreasing Fusarium Head Blight (FHB) disease on barley ( Hordeum vulgare L.). Objective and Methods: The evaluation supplied incorporated into soil as a foliar spray against four FHB species under controlled conditions was investigat...

The article examines the Democratic Progress Institute’s (DPI) Turkey program as a Track Two comparative consultation initiative applied in case of Turkey’s peace process regarding Kurdish conflict, commonly known ‘resolution/peace process’ (2012–2015). Based on interviews with high- and middle-level actors participating events organized by DPI, investigates extent reached its purposes building...

Abstract Coccidiosis is a critical enteric disease that costs more than $14.5 billion in annual cost to world poultry industry. It caused by different Eimeriaspecies invade and replicate within the intestinal epithelium site-specific manner. The Eimeriainfection induces local damage, reduces feed consumption, utilization, growth performance, increasing mortality rate. With recent antibiotic ban...

Deep packet inspection (DPI) systems are required to perform at or near network line-rate speeds, matching thousands of rules against the network traffi c. The engineering performance and price trade-offs are such that DPI is diffi cult to virtualize, either because of very high memory consumption or the use of custom hardware; similarly, a running DPI instance is diffi cult to ‘move’ cheaply t...

The identification of the nature of the traffic flowing through a TCP/IP network is a relevant target for traffic engineering and security related tasks. Despite the privacy concerns it arises, Deep Packet Inspection (DPI) is one of the most successful current techniques. Nevertheless, the performance of DPI is strongly limited by computational issues related to the huge amount of data it needs...

BACKGROUND Human African trypanosomiasis or sleeping sickness, caused by the parasite Trypanosoma brucei, leads to neuroinflammation and characteristic sleep/wake alterations. The relationship between the onset of these alterations and the development of neuroinflammation is of high translational relevance, but remains unclear. This study investigates the expression of interferon (IFN)-γ and IF...

BACKGROUND In patients receiving inhaled medication, dissatisfaction with and difficulty in using the inhaler can affect treatment adherence. The incidence of handling errors is typically higher in the elderly than in younger people. The aim of the study was to assess inhaler preference for and handling errors with the ELLIPTA® dry powder inhaler (DPI), (GSK), compared with the established BREE...

BACKGROUND In a previous study, a 200-microg once-daily evening dose of mometasone furoate dry powder inhaler (DPI) was effective in patients with asthma previously taking inhaled corticosteroids. No studies have been conducted to test the effect of a once-daily evening dose in patients previously using only short-acting beta2-adrenergic agonists (SABAs) for symptom relief. OBJECTIVE To evalu...