We investigated the role of the septo-hippocampal cholinergic projection in anxiety, spatial novelty preference, and differential reward for low rates of responding (DRL) performance. Cholinergic neurons of the rat medial septum (MS) and the vertical limb of the diagonal band of Broca (VDB) were lesioned using the selective immunotoxin, 192 IgG-saporin. Rats were then tested on several behavior...

The use of diagnostic reference levels (DRLs) is part of the optimisation process of radiation protection, in that it identifies practices that are in need of corrective action, resulting in dose reduction. Their use is provided for in Irish and European legislation. In this project, measurements were carried out at 42 of the 46 licensed intra-oral xray machines in Co. Wicklow using an Unfors M...

The linotte (lio) mutant was first isolated as a memory mutant. The lio gene encodes a putative receptor tyrosine kinase (RTK), homologous to the human protein RYK. This gene has been independently identified in a screen for embryonic nervous system axonal guidance defects and called derailed (drl). Here, we report that linotte mutants present structural brain defects in the adult central compl...

A few representations have been used for capturing design rationale. To understand their scope and adequacy, we need to know how to evaluate them. In this article, we develop a framework for evaluating the expressive adequacy of design rationale representations. This framework is built by progressively differentiating the elements of design rationale that, when made explicit, support an increas...

BACKGROUND Daytime running lights (DRLs) are a safety feature intended to reduce crashes by increasing the contrast between vehicles and the background. AIMS The purpose of this study was to determine whether there is an association between vehicles in the USA being equipped with DRLs and crash rates. METHODS This was a retrospective study using the Minnesota Department of Transportation (M...

A year ago, one thousand USD invested in Bitcoin (BTC) alone would have appreciated to three five hundred USD. Deep reinforcement learning (DRL) recent outstanding performance has opened up the possibilities predict price fluctuations changing markets and determine effective trading points, making a significant contribution finance sector. Several DRL methods been tested domain. However, this r...

BL-algebras, introduced by P.Hájek, form an algebraic counterpart of the basic fuzzy logic. In the paper it is shown that BL-algebras are the duals of bounded representable DRl-monoids. This duality enables us to describe some structure properties of BL-algebras.