results there was significant reduction in anger symptoms of drug-dependent individuals after gross model based emotion regulation training (ert) (p < 0.001). moreover, the effectiveness of the training on anger was persistent in the follow-up period. conclusions symptoms of anger in drug-dependent individuals of this study were reduced by gross model-based emotion regulation strategies trainin...

non-medical use of prescription drugs (also known as medication diversion) is a common problem in middle and low income countries where monitoring capacities and law enforcement mechanisms are not efficiently developed (1-3). prescribed central nervous system (cns) stimulants, sedative hypnotics and long-lasting opioids are the most important drugs diverted throughout the world (1-4). non-medic...

personalized medicine aims is to supply the proper drug to the proper patient within the right dose. pharmacogenomics (pgx) is to recognize genetic variants that may influence drug efficacy and toxicity. all things considered, the fields cover a wide area, including basic drug discovery researches, the genetic origin of pharmacokinetics and pharmacodynamics, novel drug improvement, patient gene...

prescriptions written by general practitioners and medical specialists were studied and compared to determine the type, time of onset and clinical importance of drug-drug interactions (ddis) in an attempt to reduce further complications. in 2007, 28, 956, 638 prescriptions and 15, 610, 912 prescriptions in 2008 were filled by pharmacies affiliated with medical science universities. these prescr...

conclusions as the results showed, the trend of activities was encouraging and some additional activities could be included to future programs relying on early-onset preventions. results summarizing the data led to three distinguished sections: 1) drug supply reduction activities; 2) drug demand reduction activities; 3) harm reduction activities. evidence acquisition in this report, authors gat...

background: due (drug utilization evaluation) studies can help identify and correct problems associated with irrational use of drugs. considering lack of data regarding how rational vancomycin is being used, we evaluated this due study in a referral infectious center to evaluate compliance with guidelines in terms of rational use of this valuable antibiotic. methods: this retrospective study wa...

benzoyl peroxide (bpo) is a first-line topical treatment in acne vulgaris, and it is superior to antibiotics, because the bacteria do not develop resistance to it. skin irritation is a common side effect, and it has been shown that controlled release of bpo from a delivery system to the skin could reduce the side effects while reducing percutaneous absorption. therefore, the purpose of the pres...

the drug pump protein mrp2 is a membrane drug efflux transporter widely distributed in normal and tumor tissues. its role is thought to be crucial for the disposition of many drugs and their substrates in different tissues. in this study, we aimed to examine the effects of systematic inflammation induced by lipopolysaccharide (lps) on the expression and function of this transporter in rats. jug...