Protein Binding One of the most important factors in drug-drug interactions is the plasma protein concentration, specifically albumin. Albumin is the major protein responsible for binding acidic drugs such as warfarin, NSAIDS and anticonvulsants. Decreases in albumin level, which are commonly seen with critical illness, can lead to an excess of unbound, and therefore more active, drug. Alpha1-a...

Background: Drug-drug interactions (DDIs) may often lead to preventable adverse drug events and health damage. Particularly in hospitals, this might be an important factor as multiple drug therapies are common. The objective of this study was to identify the frequency and levels of potential DDIs in internal medicine wards in an Iranian university hospital. Methods: A cross-sectional study...

the use of herbal medicines in diabetes is promising but still far from proven. the purpose of this article is to examine the effect of herbal medicines in the treatment of diabetes, focusing on potential benefits and risks. medline, expert interviews, books, articles and internet searches were used to identify herbal medicines with anti-diabetic properties and their diabetes-related health eff...