نتایج جستجو برای: drug nanocarriers

تعداد نتایج: 590981  

Journal: :Nanoscale 2015
Jian Chen Weijie Zhang Min Zhang Zhen Guo Haibao Wang Mengni He Pengping Xu Jiajia Zhou Zhenbang Liu Qianwang Chen

Artemisinin (ART) is a natural drug with potent anticancer activities related with Fe(2+) mediated cleavage of the endoperoxide bridge in ART. Herein, we reported that Mn(2+) could substitute for Fe(2+) to react with ART and generate toxic products, inducing a much higher anticancer efficiency. On this basis, we prepared pH-responsive Fe3O4@MnSiO3-FA nanospheres which can efficiently deliver hy...

2009
Donglu Shi

This article provides an overview on the development of integrated multifunctional nanosystems for medical diagnosis and treatment. In particular, a novel system is developed specifically for achieving simultaneous diagnosis and treatment of cancer. Critical issues are addressed on the architecture and assembly of nanocomponents based on medical requirements: targeted in vivo imaging, controlle...

2011
Vassilios Karavelidis Evangelos Karavas Dimitrios Giliopoulos Sofia Papadimitriou Dimitrios Bikiaris

Four new polyesters based on 1,3-propanediol and different aliphatic dicarboxylic acids were used to prepare ropinirole HCl-loaded nanoparticles. The novelty of this study lies in the use of polyesters with similar melting points but different degrees of crystallinity, varying from 29.8% to 67.5%, as drug nanocarriers. Based on their toxicity to human umbilical vein endothelial cells, these ali...

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