BACKGROUND In the decade after 1983, the annual growth rate of drug expenditure was about four times as high as that of per capita gross domestic product (GDP) in Shanghai. In 1993 and 1994, a drug list policy and hospital revenue capping policy were introduced in Shanghai to contain drug expenditure. We studied the impact of these two policies, as a model for similar policies in other parts of...

English. This is particularly so in the early part of the book. When making a proposal, they often examine several possibilities which are all plausible in their framework. This should be welcomed by readers with only limited exposure to formal semantics. The authors address methodological issues at several points, since their main concern is the presentation of a fragment. Nevertheless, it wou...

The approval of new medicines has slowed significantly over the past years. In order to accelerate the development of new compounds, novel approaches in drug development are required. Translational medicine or research, an emerging discipline on the frontier of basic science and medical practice, has the potential to enhance the speed and efficiency of the drug development process through the u...

Compliance with malaria chemoprophylaxis programmes was studied in the National Railways and two large commercial farm labour forces in Zimbabwe. Prophylaxis was primarily conducted using pyrimethamine/dapsone and the study measured compliance rates through interview and the detection of drug in the urine. Compliance rates as indicated from registers or questioning were not always reliable and ...

OBJECTIVES To evaluate the impact of retrospective drug utilization review (RDUR), pharmacist's interventions on physician prescribing, and the level of spillover effect on future prescriptions following the intervention. METHODS A retrospective case-control study was conducted at a pharmacy benefits management company using the available prescription data from April 2004 to August 2005. RDUR...

Drug utilization in the inpatient setting can provide a mechanism to assess drug prescribing trends, efficiency, and cost-effectiveness of hospital formularies and examine subpopulations for which prescribing habits may be different. Such data can be used to correlate trends with time-dependent or seasonal changes in clinical event rates or the introduction of new pharmaceuticals. It is now pos...

Overall drug overuse, including psychotropic, is the Croatian reality. Therefore, in between 2000 and 2012, the interventions to control drug overspending were undertaken. The main aims of the study are: to determine the morbidity trends of mental disorders registered in family medicine (FM), the trends in psychotropic drug utilization and to identify whether the trends of utilization have any ...

The application of appropriate rules for drug-drug interactions (DDIs) could substantially reduce the number of adverse drug events. However, current implementations of such rules in tertiary hospitals are problematic as physicians are receiving too many alerts, causing high override rates and alert fatigue. We investigated the potential impact of Korean national DDI rules in a drug utilization...