A 29-year-old female, an aesthetician, developed occupational allergic contact dermatitis caused by extracts of crude drugs. The results of 48-hour closed patch testing showed positive reactions to the moisturizing cream and oil that she used in her work. This cream and oil included Scutellraria Baicalensis, mugwort (Artemisia vulgaris), and Artemisia capillaris,Gardenia. The results of patch t...

According to the amended Drugs and Cosmetics Rules of the Government of India, participants in clinical trial are entitled to medical treatment and financial compensation in the event of permanent injury or death, but the quantum of compensation is to be decided by same Ethics Committee that sanctioned the trial in the first place. If there is a dispute regarding the amount of compensation the ...

The following article is based on the Symposium X presentation given by David A. Weitz (Harvard University) on April 11, 2007, at the Materials Research Society Spring Meeting in San Francisco. The article describes how simple microfluidic devices can be used to control fluid flow and produce a variety of new materials. Based on the concepts of coaxial flow and hydrodynamically focused flow, us...

The development of drugs is a process obstructed with manifold security and efficacy concerns. Although animal models are still widely used to meet the diligence required, they are regarded as outdated tools with limited predictability. Novel microphysiological systems intend to create systemic models of human biology. Their ability to host 3D organoid constructs in a controlled microenvironmen...

Arylamines are widely used in food, drugs, and cosmetics as well as other industries. These chemicals are present ubiquitously in cigarette smoke, smoke emitted from cooking fume hoods as well as are generated by diverse industries. Arylamines can be generated by cleavage of azo dyes by intestinal and skin microbiota. Some arylamines are used as drugs while others are constituents of human meta...

The majority of the currently used cosmetics and drugs are natural products-based compounds or their derivatives. This could add weight to the argument that natural based products are inherently better tolerated in the body than synthetic chemicals and have higher chance to be approved as new drugs. The present study was undertaken to analyze a natural product database compared to synthetic che...

In Europe, the safety evaluation of cosmetics is based on the safety evaluation of each individual ingredient. Article 3 of the Cosmetics Regulation specifies that a cosmetic product made available on the market is to be safe for human health when used normally or under reasonably foreseeable conditions. For substances that cause some concern with respect to human health (e.g., colourants, pres...

Preservatives prevent the growth of microorganisms in foods, pharmaceuticals and cosmetics. There exist numerous restrictions regarding the maximum allowable levels of preservatives in cosmetics. We analyzed 11 regulated preservatives in commercial cosmetics and manufacturers need to analyze their products for quality control purposes. However, methods used in previous studies to date have been...