9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (BIOLF-62) is highly synergistic with either phosphonoformate or phosphonoacetate when used in combination against herpes simplex virus types 1 and 2 in vitro. Acycloguanosine did not show significant synergism with these two compounds. Bromovinyldeoxyuridine and phosphonoformate were highly synergistic against herpes simplex virus type 2, bu...

Two series of naphtho[1,8-ef][1,4]diazepines and pyrrolo[1,2-a]perimidines were prepared starting from 1,8-diaminonaphthalene and hydrazonoyl chlorides. The structures of the products were determined on the basis of their spectral data and elemental analyses. The mechanism of formation of such products was also discussed. The prepared compounds were screened for their antitumor activity against...

UNLABELLED Epsilon toxin secreted by Clostridium perfringens types B and D has been directly implicated as the causative agent of fatal enterotoxemia in domestic animals. The aim of the present study is to use in silico approach for identification of B-cell epitope(s) of epsilon toxin, and its expression in fusion with a carrier protein to analyze its potential as vaccine candidate(s). Using di...

Jeroen Huisman is professor at the University of Bath, UK. E-mail: [email protected]. Harry de Boer is senior research associate at the University of Twente, the Netherlands. E-mail: [email protected]. Paulo Charles Pimentel Bótas is research officer at the University of Bath, UK. E-mail: [email protected]. For those interested, the full scenarios can be found in Higher Education Quar...

Beküldte Németh Gábor 2. h, 2015-01-05 11:23 Hantos N [1], Balázs P [2]. Fast Heuristics for Eliminating Switching Components in Binary Matrices by 0-1 Flips [3]. In: Bayro-Corrochano E. [4], Hancock E. [5], editors. Progress in Pattern Recognition, Image Analysis, Computer Vision, and Applications: 19th Iberoamerican Congress (CIARP). Puerto Vallarta, Mexico: Springer; 2014. 6. p. 62-69p. (LNC...