References [1] Hubel, D.H., Wiesel, T.N.: Receptive fields and functional architecture of monkey striate cortex. J. Physiol. (Lond.) 195, 215–243 (1968). [2] K. Fukushima: Neocognitron: A self-organizing neural network model for a mechanism of pattern recognition unaffected by shift in position, Biological Cybernetics, 36(4), pp. 193-202 (April 1980). [3] Riesenhuber, M. & Poggio, T. (1999). Hi...

Central MessageThe surgical management of aortic root aneurysms in congenital cardiac patients has evolved, taking cues from the adult acquired literature. However, much remains to be learned.See Article page 955. The learned. See Valve-sparing replacement (VSRR), when compared with prosthetic valve and replacement, advantages native hemodynamics, avoiding complications associated anticoagulati...

Since the start of COVID-19 pandemic in March, 2020, in-person contact with family members, friends, and colleagues has been heavily restricted. These mitigation measures can worsen pre-existing social isolation.1Cudjoe TKM Kotwal AA “Social Distancing” amid a crisis isolation loneliness.J Am Geriatr Soc. 2020; 68: e27-e29Crossref PubMed Scopus (45) Google Scholar In this phase widespread insec...

•COVID-19 positives (n = 2091) were assessed for spike gene target failure (SGTF).•The B.1.1.7 lineage was found in 93.2% of the 226 SGTF samples.•The results support local transmission since mid-December 2020. In this Journal, Tang and colleagues recently discussed emergence a new Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variant UK necessity to determine its impact on socie...

Central MessageThe incidence of late surgical and endovascular interventions may be substantial for medically managed, uncomplicated dissections the descending thoracic aorta.See Article page 958. The aorta. See Thoracic aortic repair (TEVAR) is recommended treatment patients presenting with acute type B dissection (ATBAD) that complicated by rupture or malperfusion, whereas optimal medical the...

Twelve new X chromosome duplications were identified and characterized. Eight are translocated to autosomal sites near four different telomeres, and four are free. Ten include unc-l(+), which in wild type is near the left end of the X chromosome, and two of these, mnDp72(X;ZV) and m n D p 7 3 ( X f ) , extend rightward past dpy-3. Both mnDp72 and mnDp73 recombined with the one X chromosome in m...

The present study compares the voice quality of female and male speech in two languages: Czech, a Slavic language, Danish, Germanic language. For both languages, results based on total 120 vocally healthy speakers are line with claim that females universally breathier than males. This was supported by Cepstral Peak Prominence (CPP) H1*-H2* measures, which generally known as most robust correlat...

Community Telecenters, that is centers for community development using ICT (Information and Communications Technologies), have become the focus of attention in international development circles over the past ten years, especially in Latin America. A virtual community called Somos@Telecentros is progressively taking shape in the region (http://www.tele-centros.org) with a specific interest in su...

Insulin has an important role in cognition, in addition to its well-known functions in peripheral glucose metabolism. Impaired insulin signaling has been linked to the cognitive decline seen in type 2 diabetes and Alzheimer’s Disease (de la Monte & Wands, 2008). This study examined the effect of insulin on fMRI brain activation during working memory and episodic memory tasks in six postmenopaus...