نتایج جستجو برای: e6ap
تعداد نتایج: 171 فیلتر نتایج به سال:
Cervical cancer cases caused by infection with Human Papillomavirus (HPV), especially HPV 16 (60.5% of cases) continue to increase every year a high mortality rate. The current anti-cancer drugs were not only specifically targeting cells, but healthy cells and can cause serious side effects. Therefore, it is necessary find safer alternative therapies, e.g., using active compounds from natural p...
In most cervical cancers, DNAs of high-risk mucosotropic human papillomaviruses (HPVs), such as types 16 and 18, are maintained so as to express two viral proteins, E6 and E7, suggesting that they play important roles in carcinogenesis. The carboxy-terminal PDZ domain-binding motif of the E6 proteins is in fact essential for transformation of rodent cells and induction of hyperplasia in E6-tran...
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