BACKGROUND AND PURPOSE Early ischemic changes on noncontrast CT in acute stroke include both hypoattenuation and brain swelling, which may have different pathophysiological significance. METHODS Noncontrast CT and CT perfusion brain scans from patients with suspected acute stroke <6 hours after onset were reviewed. Five raters independently scored noncontrast CTs blind to clinical data using ...

An algorithm is presented for fully automated brain tumor segmentation from only two magnetic resonance image modalities. The technique is based on three steps: (1) alternating different levels of automatic histogram-based multi-thresholding step, (2) performing an effective and fully automated procedure for skull-stripping by evolving deformable contours, and (3) segmenting both Gross Tumor Vo...

The aim of present study was to investigate the effect of trifluoperazine (TFP) on carrageenan-induced rat's paw edema in intact and adrenalectomized (ADX). TFP (0.2 and 8 mg/kg) were given intraperitoneally just before the intraplantar injection of 0.1 ml of 0.5% carrageenan solution. After four hours, paw edema was assessed by calculating the paw volume changes and extravasations of Evans blu...

Relating brain tissue properties to diffusion tensor imaging (DTI) is limited when an image voxel contains partial volume of brain tissue with free water, such as cerebrospinal fluid or edema, rendering the DTI indices no longer useful for describing the underlying tissue properties. We propose here a method for separating diffusion properties of brain tissue from surrounding free water while m...

purpose : to compare the 6-months anatomic and best corrected visual acuity (bcva) responses after primary intravitreal bevacizumab (ivb intravitreal avastin) and ivb plus macular photocoagulation (mpc) in diabetics with clinically significant macular edema (csme) methods : in this interventional randomized clinical trial (rct) 40 diabetics (80 eyes) with bilateral csme and non-proliferative di...

the brain edema is one of remarkable injuries after traumatic brain injuries (tbi). the common treatments for limiting edema are included mannitol, barbiturates, corticosteroids, hyperventilation and central nervous system derange. the most of these treatments for edema is problematic. for example, mannitol can be effective for the short period of time (24 hours) after brain injuries but is not...

Tidal volume reduction during mechanical ventilation reduces mortality in patients with acute lung injury and the acute respiratory distress syndrome. To determine the mechanisms underlying the protective effect of low tidal volume ventilation, we studied the time course and reversibility of ventilator-induced changes in permeability and distal air space edema fluid clearance in a rat model of ...

BACKGROUND AND PURPOSE Damage to the blood-brain barrier with subsequent contrast enhancement is a hallmark of glioblastoma. Non-enhancing tumor invasion into the peritumoral edema is, however, not usually visible on conventional magnetic resonance imaging. New quantitative techniques using relaxometry offer additional information about tissue properties. The aim of this study was to evaluate l...