In this report, we evaluated the efficiency of stable gene transfer into established CD8(+) human tumor antigen-specific cytotoxic T cell (CTL) lines and peripheral blood lymphocytes (PBL) by oncoretroviral and lentiviral vectors. In the oncoretroviral vector, the green fluorescent protein (GFP) reporter gene was regulated by the murine stem cell virus (MSCV) promoter. In three human immunodefi...

The recent observation by CDF of Σ±b (uud and ddb) baryons within 2 MeV of the predicted Σb−Λb splitting has provided strong confirmation for the theoretical approach based on modeling the color hyperfine interaction. We now apply this approach to predict the masses of the Ξb family of baryons with quark content usb and dsb – the ground state Ξb at 5790 to 5800 MeV, and the excited states Ξ′b a...

The aim of the present study was to investigate the expression levels of miR-146a and miR-155 in a cardiac xenograft model treated with the immunosuppressant FK506, and to construct lentiviral vectors to further study the roles of miR-146a and miR-155 in cardiac xenotransplantation. Expression levels of miR-146a and miR-155 were examined by quantitative polymerase chain reaction analysis and pr...

Quantitative real-time PCR (qRT-PCR) is a reliable and reproducible technique for measuring and evaluating changes in gene expression. The most common method for analyzing qRT-PCR data is to normalize mRNA levels of target genes to internal reference genes. Evaluating and selecting stable reference genes on a case-by-case basis is critical. The present study aimed to facilitate gene expression ...

We consider families of theories with large N = 4 superconformal symmetry. We define an index generalizing the elliptic genus of theories with N = 2 symmetry. In contrast to the N = 2 case, the new index constrains part of the non-BPS spectrum. Motivated by aspects of the AdS/CFT correspondence we study the index in the examples of symmetric product theories. We give a physical interpretation o...

Za model vodiËa i feromagnetske ploËe napravljen je 3D proraËun magnetskog polja pomoÊu integralnih jednadæbi za kvazistatiËki sluËaj. Usporeeni rezultati proraËuna i mjerenja dobro se slaæu. Pristup preko integralnih jednadæbi pokazuje se vrlo efi kasnim u prostoru u kojem se traæi polje daleko od izvora i u kojem nema puno razliËitih feromagnetskih materijala. Pri tome se pretpostavlja da su...

We consider families of theories with large N = 4 superconformal symmetry. We define an index generalizing the elliptic genus of theories with N = 2 symmetry. In contrast to the N = 2 case, the new index constrains part of the non-BPS spectrum. Motivated by aspects of the AdS/CFT correspondence we study the index in the examples of symmetric product theories. We give a physical interpretation o...

Pre-eclamptic toxaemia (PET) may be associated with both endothelial dysfunction (ED) and sleep-disordered breathing (SDB). It was hypothesised that females with PET would demonstrate both SDB and ED, and that a correlation between these two would suggest a potential causative association. A total of 17 females with PET and 25 matched females with uncomplicated pregnancy were studied. They unde...

We discuss the action of SL(2,Z) on local operators in D = 4, N = 4 SYM theory in the superconformal phase. The modular property of the operator’s scaling dimension determines whether the operator transforms as a singlet, or covariantly, as part of a finite or infinite dimensional multiplet under the SL(2,Z) action. As an example, we argue that operators in the Konishi multiplet transform as pa...