TRPA1 (transient-receptor-potential-related ion channel with ankyrin domains) is a direct receptor or indirect effector for a wide variety of nociceptive signals, and thus is a compelling target for development of analgesic pharmaceuticals such as channel blockers. Recently, the structure of TRPA1 was reported, providing insights into channel assembly and pore architecture. Here we report whole...

We find that curvature-driven growth of pores in electrically charged membranes correctly reproduces charge-pulse experiments. Our model, consisting of a Langevin equation for the time dependence of the pore radius coupled to an ordinary differential equation for the number of pores, captures the statistics of the pore population and its effect on the membrane conductance. The calculated pore r...

Sediment toxicity can be assessed by conducting pore-water toxicity assays with standard water column organisms. Several methods have been developed for sampling pore-water. Centrifugation and pressurization methods are recommended when large volumes of pore-water are required to perform toxicity assays. Nevertheless, these methods involve sediment transportation and storage in laboratory, whic...

Keywords: Solar energy Solar fuels Heat and mass transfer Porous media Computed tomography Morphology a b s t r a c t The performance of high-temperature solar reactors incorporating porous ceramic materials that serve as radiative absorbers and chemical reaction sites can be improved significantly by tailoring their pore structure. We investigated the changes in their effective heat and mass t...

A computer algorithm is implemented to construct 3D cubic pore networks that simultaneously honor nuclear magnetic resonance (NMR) and mercury injection capillary pressure (MICP) measurements on core samples. The algorithm uses discretized pore-body size distributions from NMR and pore-throat size vs. incremental pore-volume fraction information from MICP as initial inputs. Both pore-throat rad...

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Simulation of effective physical properties from microtomographic 3D images of porous structures allows one to relate properties of rocks directly to their microstructure. A static FEM code has been previously used to estimate effective elastic properties of fully saturated monomineralic (quartz) rock under wet and dry conditions. We use the code to calculate elastic properties under partially ...

nanoporous anodic aluminum oxide (aao) has been used in many different fields of science and technology, due to its great structural characteristics. solar selective surface is an important application of this type porous material. this paper investigates the effect of nanoporous aao properties, including; film thickness, pore area percentage and pore diameter, on absorption spectra in the rang...

solute transport processes are affected by soil pore water velocity distribution. pore size distribution, which can be used to infer pore water velocity distribution, can be estimated from a soil water retention curve (n). in this study, a solute breakthrough curve was simulated using soil hydraulic parameters in four different soils. to evaluate the proposed model, predictions were compared to...

This study elucidates the relationship between membrane properties and the rejection of trace organic contaminants (TrOCs) in forward osmosis (FO). An asymmetric cellulose triacetate (CTA) and a thin-film composite (TFC) polyamide FO membrane were used for this investigation. The effective average pore radius (rp), selective barrier thickness over porosity parameter (l/ε), surface charge, suppo...