Alternative splicing can yield manifold different mature mRNAs from one precursor. New findings indicate that alternative splicing occurs much more often than previously assumed. A major goal of functional genomics lies in elucidating and characterizing the entire spectrum of alternative splice forms. Existing approaches such as EST-alignments focus only on the mRNA sequence to detect alternati...

Substituted pyrroles are an essential class of heterocyclic compounds. In this research, an efficient and eco-friendly method has been developed for the synthesis of pyrrole derivatives from the reaction of 2,5-hexanedione and primary amines. Magnetic nanoparticles supported on functionalized. 7-aminonaphthalene-1,3-disulfonic acid-functionalized. silica (Fe3O4@SiO2@Propyl–ANDSA) has been inves...

  Selecting an effective project plan is a significant area in the project management. The present paper introduces a technique to identify the project plan efficient frontier for assessing the alternative project plans and selecting the best plan. The efficient frontier includes two criteria: the project cost and the project time. Besides, the paper presents a scheme to incorporate Directed Ac...

Abstract—Keyword Search is known as a user-friendly alternative for structured languages to retrieve information from graph-structured data. Efficient retrieving of relevant answers to a keyword query and effective ranking of these answers according to their relevance are two main challenges in the keyword search over graph-structured data. In this paper, a novel scoring function is proposed, w...

In this paper, we propose a novel search algorithm called band search that generalizes guided depth-first and best-first searches. The search allocates a band of at most W nodes in each level of the search tree for storing active nodes in that level, D priority lists, one for each level, for storing overflow nodes, and D counters, one for each level, for keeping track of and to limit the degree...

Given a large set of measurement sensor data, in order to identify a simple function that captures the essence of the data gathered by the sensors, we suggest representing the data by (spatial) functions, in particular by polynomials. Given a (sampled) set of values, we interpolate the datapoints to define a polynomial that would represent the data. The interpolation is challenging, since in pr...

Marine ecosystems cover more than 70% of the globe's surface. These habitats are occupied by a great diversity of marine organisms that produce highly structural diverse metabolites as a defense mechanism. In the last decades, these metabolites have been extracted and isolated in order to test them in different bioassays and assess their potential to fight human diseases. Since traditional extr...

The safety of the Java Virtual Machine is founded on bytecode verification. Although verification complexity appears to roughly correlate with program size in the average case, its worst-case behavior is quadratic. This can be exploited for denial-of-service attacks using relatively short programs (applets or agents) specifically crafted to keep the receiving virtual machine’s verifier busy for...