In living cells, mechanochemical coupling represents a dynamic means by which membrane components are spatially organized. An extra-ordinary example of such coupling involves curvature-dependent polar localization of chemically-distinct lipid domains at bacterial poles, which also undergo dramatic reequilibration upon subtle changes in their interfacial environment such as during sporulation. H...

This paper presents a detailed Finite Element Analysis study of the formation and evolution of wrinkle pattern that observed in stretched thin membranes. The model problem is set up under the various load conditions. As a precondition for wrinkling, development of compressive stresses in the transverse direction is found to depend on both the length-to-width aspect ratio & thickness of the rect...

Thin-walled tube bending has common applications in the automobile and aerospace industries. The rotary-draw-bending method is a complex physical process with multi-factor interactive effects and is one of the advanced tube forming processes with high efficiency, high forming precision, low consumption and good flexibility for bending angle changes. However, it may cause a wrinkling phenomenon,...

Our previous studies strongly indicated that the up-regulated activity of skin fibroblast-derived elastase plays a pivotal role in wrinkling and/or sagging of the skin via the impairment of elastic fiber configuration and the subsequent loss of skin elasticity. Fortunately, we succeeded in identifying human skin fibroblast-derived elastase as a previously known enzyme, neprilysin or neutral end...

We present a combined analytical approach and numerical study on the stability of a ring bound to an annular elastic substrate, which contains a circular cavity. The system is loaded by depressurizing the inner cavity. The ring is modeled as an Euler–Bernoulli beam and its equilibrium equations are derived from the mechanical energy which takes into account both stretching and bending contribut...

Hutchinson approach has been successfully used by a number of researchers in thin sheet metal forming processes for wrinkling prediction. However, Hutchinson approach is limited to regions of the sheet that are free of any contact. Therefore, a new wrinkling indicator that can be used in the contact areas is proposed. Discretisation error indicators are also used to present a comprehensive appr...

Abstract Wrinkling instabilities occur when a stiff thin film bonded to an elastic substrate undergoes compression. Regardless of the nature compression, this phenomenon has been extensively studied through local models based on classical continuum mechanics. However, experimental behavior is not yet fully understood and influence nonlocal effects remains largely unexplored. The objective paper...

Cutis laxa is a rare disease characterized by abnormal skin wrinkling and laxity, due to decreased elastin synthesis or structural extracellular matrix defects. We have explored elastin metabolism in a case of adult onset cutis laxa localized to the upper body of a woman. For this purpose, we obtained skin biopsies from affected and unaffected skin areas of the patient and analyzed these with m...

Elastic capsules, prepared from droplets or bubbles attached to a capillary (as in a pendant drop tensiometer), can be deflated by suction through the capillary. We study this deflation and show that a combined analysis of the shape and wrinkling characteristics enables us to determine the elastic properties in situ. Shape contours are analyzed and fitted using shape equations derived from nonl...