نتایج جستجو برای: electron beam gold nanoparticle dose enhancement geant4

تعداد نتایج: 909612  

2016
Harold N. McQuaid Mark F. Muir Laura E. Taggart Stephen J. McMahon Jonathan A. Coulter Wendy B. Hyland Suneil Jain Karl T. Butterworth Giuseppe Schettino Kevin M. Prise David G. Hirst Stanley W. Botchway Fred J. Currell

Gold nanoparticle radiosensitization represents a novel technique in enhancement of ionising radiation dose and its effect on biological systems. Variation between theoretical predictions and experimental measurement is significant enough that the mechanism leading to an increase in cell killing and DNA damage is still not clear. We present the first experimental results that take into account ...

G.R. Kiani, G.R. Mahdavinia K. E. Geckeler L. Saghatforoush

Gold nanoparticles were synthesized by chemical reduction of HAuCl4 inside the pores of a polycarbonate-based membrane followed by dissolving the membrane in dichloromethane and further sonication. Sonication time as the main affecting factor on the nanoparticle size was investigated. The characterization by transmission electron microscopy showed the formation of gold nanoparticles with diamet...

Journal: :International journal of radiation oncology, biology, physics 2015
Neeharika Sinha Gizem Cifter Erno Sajo Rajiv Kumar Srinivas Sridhar Paul L Nguyen Robert A Cormack G Mike Makrigiorgos Wilfred Ngwa

PURPOSE Recent studies show promise that administering gold nanoparticles (GNP) to tumor cells during brachytherapy could significantly enhance radiation damage to the tumor. A new strategy proposed for sustained administration of the GNP in prostate tumors is to load them into routinely used brachytherapy spacers for customizable in situ release after implantation. This in silico study investi...

Journal: :Optics letters 2007
L Malic B Cui T Veres M Tabrizian

We explore periodic gold nanoposts as substrates for the enhanced surface plasmon resonance imaging (SPRi) detection of DNA hybridization. Rigorous coupled-wave analysis was used to model and design the nanopost-based SPRi biosensor. Arrayed gold nanoposts on gold-coated glass substrate, with various widths and periodicity, were fabricated using electron-beam lithography and characterized with ...

Hadi Keivan Mohammad Ali Behrooz Mohammad Javad Tahmasebi Birgani,

Introduction: Treatment with megavoltage electron beams is ideal for irradiating superficial tumors because of their limited range in tissues. However, for electron treatment of extended areas, such as the chest wall, two or more adjacent fields can be used. Abutment of these fields may lead to significant dose in homogeneities in the junction region. The aim of this study is to offer a new met...

G.R. Kiani, G.R. Mahdavinia K. E. Geckeler L. Saghatforoush

Gold nanoparticles were synthesized by chemical reduction of HAuCl4 inside the pores of a polycarbonate-based membrane followed by dissolving the membrane in dichloromethane and further sonication. Sonication time as the main affecting factor on the nanoparticle size was investigated. The characterization by transmission electron microscopy showed the formation of gold nanoparticles with diamet...

Journal: :iranian journal of medical physics 0
mohammad taghi bahreyni toossi professor, medical physics research center, bu-ali research institute, mashhad university of medical sciences, mashhad, iran mehdi momen nezhad ph.d., linear accelerator dept., imam reza hospital, mashhad university of medical sciences, mashhad, iran seyed mohammad hashemi m.sc., medical physics research center, mashhad university of medical sciences, mashhad, iran

introduction: in recent decades, several monte carlo codes have been introduced for research and medical applications. these methods provide both accurate and detailed calculation of particle transport from linear accelerators. the main drawback of monte carlo techniques is the extremely long computing time that is required in order to obtain a dose distribution with good statistical accuracy. ...

2016
Subramaniyan Bharathiraja Panchanathan Manivasagan Nhat Quang Bui Yun-Ok Oh In Gweon Lim Suhyun Park Junghwan Oh

Astaxanthin, a kind of photosynthetic pigment, was employed for gold nanoparticle formation. Nanoparticles were characterized using Ulteraviolet-Visible (UV-Vis) spectroscopy, transmission electron microscopy, and X-ray diffraction, and the possible presence of astaxanthin functional groups were analyzed by Fourier transform infrared spectroscopy (FTIR). The cytotoxic effect of synthesized nano...

ژورنال: سنجش و ایمنی پرتو 2014

In this paper, graphite calorimeter device which is using to calibrate the electron beam of therapy accelerators in the range of the low dose was simulated using the EGS4 calculation code. Then, the electron beam dose distributions were calculated in it and the effects of parameters such as thickness of the calorimeter core, the distance to the source, thickness of air gap around the core, thic...

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