We carried out a cross sectional study to analyze hemodynamic parameters of single-chamber ventricular pacemaker compared with dual-chamber pacemaker by using thoracic electrical bioimpedance monitoring method (Physio FlowTM) a novel simple non-invasive measurement. A total of 48 consecutive outpatients comprised of 27 single chamber pacemaker and 21 dual chamber were analyzed. We measured card...

BACKGROUND Severe postoperative conduction disturbances requiring permanent pacemaker implantation frequently occur following cardiac surgery. Little is known about the long-term pacing requirements and risk factors for pacemaker dependency in this population. METHODS We performed a systematic review of the literature addressing rates and predictors of pacemaker dependency in patients requiri...

Introduction Persistent left superior vena cava (PLSVC) is a congenital developmental abnormality of the sinus venosus with an incidence of 0.47% in patients undergoing cardiac implantable electronic devices. The 2 variants include a double superior vena cava (right and left SVC, with or without an innominate vein connecting the two) or a single left-sided SVC (without a right SVC), which may o...

Expanding clinical indications of cardiac rhythm management have led to an increased use of pacemaker implantation which is associated with increased incidence of pacemaker infections. Staphylococcus aureus and epidermidis account for the majority of pacemaker infections. Infection of implantable cardiac devices by mycobacterium species, particularly mycobacterial tuberculosis is rare. We prese...

T HIS report has a threefold purpose: (1) to describe a simple, clinical method of estimating myocardial threshold in patients with artificial pacemakers, (2) to verify the importance of critically high threshold as a significant cause of “pacemaker failure,” and (3) to suggest for this type of failure a nonsurgical method of restoring myocardial responsiveness by administration of glucocortico...

It has been shown that the hyperpolarization-activated current “if” that is blocked by 2 mM Cs+ plays a minor role on pacemaker activity of the center and a major role on activity of the periphery of rabbit intact sino-atrial node. On the other hand some investigations showed that if the atrial muscle, surrounding the sino-atrial node, is cut away there is a shift in leading pacemaker site from...

inhibition of pacemaker output in pacemaker-dependent patients and/or false triggering with tracking to the upper rate limit in patients with reduced left ventricular function may be detrimental. Therefore, we cannot support the approach of Martin and co-workers—that is, to leave the pacemaker sensing function activated. In contrast, we recommend deactivating the sensing function in pacemaker-d...

In 1971 Cramer [1] reported the characteristics of unambiguous measurement of sino-atrial conduction time, unipolar electrograms recorded in vitro from the pacethe identification of pacemaker shifts and the extent to maker region of the rabbit sinus node and subsequently which atrial impulses penetrate the node and act on the published similar records from the sinus pacemaker of the pacemaker. ...

The purpose of this paper is to summarize the need, feasibility, safety, legality, and ethical perspectives of pacemaker reutilization in low- and middle-income countries (LMICs). It will also describe, in-depth, Project My Heart Your Heart (PMHYH) as a model for pacemaker reuse in LMICs. The primary source of the discussion points in this paper is a collection of 14 publications produced by th...

Class I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations Selective pharmacological inhibition of the pacemaker channel isoforms (HCN1-4) as new possible therapeutical targets A multi-scale investigation of repolarization variability and its role in cardiac arrhythmogenesis Novel blockers of hyperpolarization-activated current with isoform...