Electrospinning has recently emerged as a leading technique for generating biomimetic scaffolds made of synthetic and natural polymers for tissue engineering applications. In this study, we compared collagen, gelatin (denatured collagen), solubilized alpha-elastin, and, as a first, recombinant human tropoelastin as biopolymeric materials for fabricating tissue engineered scaffolds by electrospi...

Cell adhesion in three-dimensional scaffolds plays a key role in tissue development. However, stem cell behavior in electrospun scaffolds under perfusion is not fully understood. Thus, an investigation was made on the effect of flow rate and shear stress, adhesion time, and seeding density under direct perfusion in polycaprolactone electrospun scaffolds on human dental pulp stem cell detachment...

We developed a novel technique enabling determination of the permeability of electrospun yarns composed of hundreds of fibers. Analyzing the wicking kinetics in a yarn-in-a-tube composite conduit, it was found that the kinetic is very specific. The liquid was pulled by the capillary pressure associated with the meniscus in the tube while the main resistance comes from the yarn. Therefore, one c...

In this study, Poly (L-lactic acid)/Captopril composite nanofiber membranes were electrospun for drug delivery. Different mass fractions of Poly (L-lactic acid), different ratios of Captopril and the influences of PEG4000 added in the spinning solution are discussed. The morphology, chemical components, the surface areas and pore sizes, wettability of the composite nanofiber membranes were inve...

A combination of the unique hosting properties of cyclodextrins (CDs) and the peculiar UV-responsive trans–cis isomerization of the guest molecule azobenzene has endowed light-responsibility of the inclusion complex (IC). The IC of 4-aminoazobenzene (AAB) and hydroxypropyl-b-cyclodextrin (HPbCD), with its inherent viscosity from hydrogen bondings between CDs and p–p stacking between AABs, was e...

Electrospinning is a convenient method to produce nanofibers with controlled diameters on the order of tens to hundreds of nanometers. The resulting nonwoven fiber mats are lightweight, highly porous, and have high specific surface areas around 1 to 100 m/g. Combined with the high electrical conductivity of intrinsically conductive polymers, conductive electrospun fiber mats are promising for a...

Electrospun membranes were studied for the chemical deactivation of threat agents by means of enzymatic proteins. Protein loading and the surface chemistry of hybrid nanofibers influenced the efficacy by which embedded enzymes could digest the substrate of interest. Bovine serum albumin (BSA), selected as a model protein, was electrospun into biologically active fibers of poly(vinyl alcohol), P...

In this study, preparation and application of novel biocomposite materials for textile dye removal which are produced by immobilization of specific bacteria onto electrospun nanofibrous webs are presented. A textile dye remediating bacterial isolate, Clavibacter michiganensis, was selected for bacterial immobilization, a commercial reactive textile dye, Setazol Blue BRF-X, was selected as the t...