More than 100 years of research has now been conducted into the prevention, control and elimination of rabies with safe and highly efficacious vaccines developed for use in human and animal populations. Domestic dogs are a major reservoir for rabies, and although considerable advances have been made towards the elimination and control of canine rabies in many parts of the world, the disease con...

In this study, ZnO/TiO2 and ZnO/Nb2O5 photocatalysts were evaluated in the river pollution remediation wastewater treatment from textile factories, thus, target pollutants selected for study enteropathogenic bacteria commercial dyes. The mixed oxide systems extensively analyzed order to explore their physicochemical properties. From analysis, it was found that coupling of two oxides did not mod...

Abstract Cancer stem cells (CSCs) are regarded as essential targets to overcome tumor progression and therapeutic resistance; however, practical targeting approaches limited. Here, we identify testis-specific Y-like protein 5 (TSPYL5) an upstream regulator of CSC-associated genes in non-small cell lung cancer cells, suggest a target for CSC elimination. TSPYL5 elevation is driven by AKT-depende...

environmental management for malaria control is defined as any planned physical activities that through transformation of land, water and vegetation will result in the prevention, reduction or elimination of malaria. in planning and implementing these activities, full consideration must be given to their long-term effects and benefits and to the preservation of the quality of environment and th...

The paper studied the noise elimination methods for the signals observed from a self-mixing-laser diode (SMLD) based sensing system. The core part of the sensing system consists of a LD, a lens and an external vibrating target. The proposed noise elimination methods are applied on both the simulated and experimental sensing signals. The results presented in the paper show the noise contained in...

Nitrones undergo dynamic exchange in chloroform at room temperature through two mechanisms-hydrolysis and recombination or hydroxylamine addition/elimination; this dynamic exchange is harnessed to select a nitrone-based bis(amidopyridine) receptor for diacids from a group of four nitrones through its binding to a glutaric acid-based target.

With the goal of eventually synthesizing [5]radialene (3), the still missing member of the parent radialene hydrocarbons, we have prepared the pentaacetates 21 and 31, the pentabromide 29 and the hexabromide 32. In principle these should be convertible by elimination reactions to the desired target molecule.

α-Methylacyl-CoA racemase (AMACR; P504S) regulates branched-chain fatty acid degradation, activates Ibuprofen and is a recognised cancer drug target. A novel, facile colorimetric assay was developed based on elimination of 2,4-dinitrophenolate. The assay was used to test 5 known inhibitors, determining IC50 and Ki values, reversibility and characterizing irreversible inhibition.