A 36 year old patient underwent in-vitro fertilization (IVF) and embryo transfer. Three embryos were transferred to her uterus and eight spare embryos were cryopreserved. The patient conceived a quadruplet pregnancy and delivered two boys and two identical twin girls by Caesarean section at 30 weeks gestation. The couple subsequently donated their cryopreserved embryos to the embryo donation pr...

Abstract Study question Does oral dydrogesterone (OD) in luteal phase support (LPS) provide equivalent clinical pregnancy and miscarriage rates as micronized vaginal progesterone (MVP) oocyte donation recipients? Summary answer No significant difference was observed when using OD instead of MVP for LPS donation. What is known already Dydrogesterone has a higher bioavailability than due to its h...

introduction: to draw a general picture of the current iranian-law and shiah fiqh position as to the assisted reproduction: -whether allowed or not, - and, to show how and what changes could occur in this field. materials and methods: examination of the iranian legislation and judicial decisions, consideration of jurisprudential verdicts of the eminent shiah jurists and interpretation of the or...

BACKGROUND Several evidences indicate that premature luteinization (PL) may affect IVF outcome. The primary end-point of the present study was to verify the effect of PL on the pregnancy rate (PR) of our oocyte-donation programme. METHODS PL was defined as serum progesterone > or = 1.2 ng/ml on the day of HCG. We analysed retrospectively 240 oocyte-donation cycles in which 120 women donated t...

Gamete and embryo donation, although technically fairly straightforward, are psychologically, emotionally and socially complex, having significant impact on parents and donor offspring. The activity follows a pathway that can be distinguished in multiple phases, each characterized by specific choices and dilemmas for which no standard solutions are available (Figure 1). The expectations, belief...

The morphology of fertilization events has been related to successful implantation by subjective criteria (pronuclei score, pronuclei symmetry and position). This work first described these events by time-lapse technology and then compared the timings of fertilization events (second polar body extrusion, first and second pronuclei appearance, abuttal and fading) in implanted versus nonimplanted...

OBJECTIVE The objective of this prospective randomised study was to evaluate if there is an improvement in clinical outcomes when assisted hatching (AH) is performed in embryos derived from vitrified/warmed oocytes in an ovum donation programme using egg cryobanking. STUDY DESIGN Sixty oocyte recipients in a donation programme using egg cryobanking were randomly allocated to the assisted hatc...