25 Temporary deafferentation of the upper limb, with ischemic or anesthetic nerve block, has 26 rapid effects on sensorimotor cortex. Cutaneous anesthesia of the forearm has recently been 27 found to improve sensory and motor function of the paretic hand in chronic stroke patients. 28 However, the neurophysiological mechanisms are unknown. The aim of this study was to 29 investigate the behavio...

OBJECTIVE Circumcision is a commonly performed surgical procedure but choice of anesthesia remained an issue of research and debate. This study was conducted to find out the effectiveness of the eutectic mixture of local anesthetic (EMLA) cream with dorsal penile nerve block (DPNB) using lignocaine, for reduction of pain during circumcision. METHODOLOGY This was comparative study carried out ...

Background: Pain is a both sensory and an emotional experience when untreated unrecognized, it extracts significant physiological, biochemical psychological toll on the children family members. Vaccine injections are considered to be most common cause of iatrogenic pain in childhood. Positive during vaccine injection like reducing with local anaesthetics can avoid pre procedural anxiety future,...

OBJECTIVES The aim of the present study was to elucidate the mechanism of cutaneous vasodilation following acupuncture stimulation by investigating the roles of nitric oxide (NO) and axon reflex vasodilation. METHODS The subjects were 17 healthy male volunteers. The role of NO was investigated by administering N(G)-nitro-l-arginine methyl ester hydrochloride (L-NAME, 20 mM), an NO synthase in...