OBJECTIVES To examine the immunohistochemical expression of cyclooxygenase-2 (COX-2) and nuclear factor-κB (NF-κB) in benign endometrial polyps (EPs), endometrial hyperplasia (EH), endometrial intraepithelial neoplasia (EIN), and endometrioid endometrial cancer (EC). METHODS The immunohistochemical expression of COX-2 and NF-κB was performed using an Aperio Scanscope XT automated system in 21...

Breast cancer is among the commonest malignant diseases in women. Over the past two decades tamoxifen has been generally accepted as an endocrine therapy of choice for prevention of breast cancer recurrence. Although tamoxifen was thought to have only a few adverse effects, several reports indicate that it is associated with an increase incidence of proliferative and neoplastic changes in the e...

Objective: To study the prevalence of various histopathological changes, patterns and lesions endometrium in women with postmenopausal bleeding. Methodology: All fixed specimens were processed embedded paraffin wax. Multiple serial sections 4-5 microns thickness obtained from block then stained H & E. The observations our analyzed using SPSS software version 11.5. average values are statist...

Objective To evaluate the accuracy of transvaginal ultrasonography, hysteroscopy and uterine curettage in the diagnosis of endometrial polyp, submucous myoma and endometrial hyperplasia, using as gold standard the histopathological analysis of biopsy samples obtained during hysteroscopy or uterine curettage. Methods Cross-sectional study performed at the Hospital Universitário de Brasília (HUB)...

Adenomyosis, also known as endometriosis interna, is the presence of endometrial glands and stroma within the myometrium. Its localised form is called adenomyoma and mimics a leiomyoma. Rarely, adenomyomas are located outside the uterus and some of them form uterus-like masses with a thick muscle wall and an endometrium-lined central cavity. They are generally located in the ovary or broad liga...

27 Background. The objectives of this study were to determine the effectiveness the 28 effectiveness of post-polypectomy hysteroscopic endometrial resection in preventing the 29 recurrence of endometrial polyps in post-menopausal patients and analyse the 30 complications and necessity of additional surgery in patients, in addition to their degree 31 of satisfaction. 32 Methods. A prospective lo...

Hysterosonography (SHG) is a new noninvasive technique that involves the slow infusion of sterile saline solution into the uterus during ultrasound imaging. Expansion of endometrial cavity by SHG allows optimal visualization and plays an important role in the evaluation of abnormalities related to the uterus. The most common indications for hysterosonography are: abnormal uterine bleeding both ...