Gastrointestinal endometriosis-associated malignancies are rare and diagnostically challenging. Mullerian endometrioid adenocarcinoma is the most common and likely to be confused with a primary colonic adenocarcinoma due to their overlapping histological features. We present a case of mullerian endometrioid adenocarcinoma arising from colonic endometriosis in a 61year-old woman who presented wi...

The article presents a clinical case of patient with histologically confirmed cyst the canal Nuck, similar at preoperative stage according to anamnestic, instrumental, objective data an endometrioid inguinal canal.

background: this study was designed to determine the frequency of microsatellite instability (msi) in young iranian pa­tients with endometrial carcinoma and to evaluate its association with histopathologic and clinical features of disease. methods : microsatellite status was analyzed in 23 patients with endometrioid type endometrial cancer who were less than 55 years. clinicopathologic characte...

Endometrial cancer is one of the most common gynaecological malignancies worldwide. Histologically, two types endometrial with morphological and molecular differences also therapeutic implications have been identified. Type I has an endometrioid morphology estrogen-dependent, while II appears non-endometrioid differentiation follows estrogen-unrelated pathway. Understanding biology genetics cru...

Objectives This is a protocol for Cochrane Review (diagnostic). The objectives are as follows: To assess the diagnostic accuracy of potential screening tests detection atypical hyperplasia (pre‐cancer) and endometrial cancer all stages grades in asymptomatic (healthy) women general population. Secondary determine optimal thickness cut‐off value using transvaginal ultrasound scan hyperplasia. in...

Retrorectal lesions are rare entities. We report the complete clinicopathological details of an unusual retrorectal lesion composed of low-grade endometrioid adenocarcinoma and propose that this is a malignant change in pluripotent cells arising within a long-standing retrorectal tailgut lesion. To the best of our knowledge, this is the first case report of this malignancy in a retrorectal tail...

The aim of the study was to determine the frequency and pathohistological features of endometrial hyperplasia and carcinoma in premenopausal and postmenopausal patients with abnormal uterine bleeding (AUB). The frequency and pathohistological features of endometrial hyperplasia and carcinoma were investigated in 961 patients with AUB who underwent dilatation and curettage (D&C) between January ...

Inhibins/activins are secreted polypeptides of the transforming growth factor-β superfamily, forming a family of dimeric, disulphide-linked proteins. Inhibins are composed of an α-subunit and one of two possible β-subunits. Both inhibins and activins have substantial roles in human reproduction and in endocrine-responsive tumors. However, the prognostic significance and clinical implications of...

We investigated the distribution of endometrial lymphatic vessels and expression of forkhead box C2 (FOXC2) in normal endometrium during menstrual cycle and in endometrial adenocarcinoma. Full-thickness uterine samples and endometrial adenocarcinoma samples were collected for immunohistochemical analysis using D2-40 and FOXC2 mouse monoclonal antibodies. The lymphatic vessel density (LVD) of th...