BACKGROUND To compare efficacy of simvastatin with GnRHa (Decapeptyl 3.75 mg) on endometriosis-related pains following surgery for endometriosis. MATERIAL/METHODS Sixty women with pelvic endometriosis, after laparoscopic diagnosis and conservative laparoscopic surgery, were treated with either simvastatin (n=30) for 16 weeks or Decapeptyl (n=30) every 4 weeks for 4 doses. RESULTS Using VAS,...

STUDY OBJECTIVE To assess feasibility, and collect preliminary data for a subsequent randomized, sham-controlled trial to evaluate Japanese-style acupuncture for reducing chronic pelvic pain and improving health-related quality of life (HRQOL) in adolescents with endometriosis. DESIGN Randomized, sham-controlled trial. SETTINGS Tertiary-referral hospital. PARTICIPANTS Eighteen young women...

INTRODUCTION. Endometriosis is a disease characterized by the presence of tissue that is histologically identical to endometrium at ectopic locations outside the uterine cavity and protean manifestations. The incidence of endometriosis is strongly influenced by the awareness of non-classical lesions and because of the long-standing interest of the group in these lesions. The prominent symptoms ...

Vascular endothelial growth factor (VEGF) serum levels and VEGF and cellular expression were prospectively analyzed in 60 patients (group A consisted of asymptomatic patients or patients presenting mild dysmenorrhea; 30 women comprised group B severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation ...

endometriosis is a common gynaecological disease that can cause severe pelvic pain such as dysmenorrhoea and dyspareunia, however the mechanisms by which pain is generated are not well understood. nerve fibres in endometriotic plaques have been reported by several authors. we have recently demonstrated the presence of unmyelinated sensory nerve fibres (using the pan-neuronal marker pgp9.5) in t...

scar endometriosis is a rare form of extra-pelvic endometriosis that can occur after surgery involving the uterus. direct mechanical implantation seems to be the most conceivable theory for scar endometriosis. patient usually presents with lump and pain at surgical site. often the diagnosis of endometriosis is not suggested until histology has been performed. we hereby present a case of scar en...

Endometriosis is a common disease in up to 10% of women of reproductive age. It often causes symptoms such as dysmenorrhea, chronic pelvic pain, dyspareunia and dyschezia [1]. It is also associated with ovarian endometrioma which requires surgery for both diagnosis and treatment. However, recurrence rates are approximately 30-50% within 5 years after surgery [2]. Dienogest is a new synthetic or...

STUDY QUESTION Is there any benefit to including the routine examination by ultrasound of the bladder, ureters and kidneys of women with endometriosis? SUMMARY ANSWER The benefit of examination of the complete urinary tract of women with suspected endometriosis is that ureteric endometriosis, with or without hydronephrosis, can be detected which facilitates early intervention to prevent nephr...

Chronic pelvic pain is one of the most challenging gynecologic problems seen in primary care practice. Important causes of this problem include endometriosis, pelvic adhesions, chronic pelvic inflammatory disease, and the syndrome of chronic pelvic pain without obvious pathology. The diagnostic approach to chronic pelvic pain begins with a careful medical history and physical examination in con...

Endometriosis remains a cause of significant morbidity in reproductive-aged women resulting in pelvic pain, pelvic masses, and infertility. Endometriosis is defined as the presence of endometrial glands and stroma outside of their normal intrauterine location, most commonly in the dependent portions of the pelvis. Endometriosis is treated with medical therapies, surgery or both. The medical the...