Innate lymphoid cells (ILCs) are key regulators of tissue homeostasis, inflammation, and immunity to infections. ILCs rapidly respond environmental cues such as cytokines, microbiota invading pathogens which regulate their function phenotype. Even though rare cells, they enriched at barrier surfaces the gastrointestinal (GI) tract, often critical host’s immune response eliminate pathogens. On o...

BACKGROUND Diarrhea is one of the leading causes of mortality in young children. Diarrheal pathogens are transmitted via the fecal-oral route, and for children the majority of this transmission is thought to occur within the home. However, very few studies have documented enteric pathogens within households of low-income countries. METHODS AND FINDINGS The presence of molecular markers for th...

Members of the genus Campylobacter are well recognised as enteric pathogens but have rarely been implicated as human placental pathogens. A case of septic abortion due to C jejuni is reported. This occurred in a previously healthy woman with a diarrhoeal illness. The presence of chorioamnionitis raises the possibility of ascending infection rather than septicaemic spread as the pathogenesis. Me...

This report describes cyclosporiasis in a seven month old infant who presented with incessant crying and refusal of feeds. The routine modified ZN stained smears showed the oocysts of Cyclospora when all other tests failed to reveal enteric pathogens. The need for the clinical laboratory to screen faeces samples for all possible pathogens in a given clinical situation needs to be emphasized.

Worldwide, enteric infections are the second commonest cause of disease burden due to all infectious diseases. It is estimated that they are responsible for 1.3 million deaths per year, mostly in children below 5 years of age in the developing world. Enteric infections are caused by a gamut of bacterial, viral and parasitic agents. These include viruses (rotaviruses, enteric adenoviruses, astro...

Enteric infections, with or without overt diarrhea, have profound effects on intestinal absorption, nutrition, and childhood development as well as on global mortality. Oral rehydration therapy has reduced the number of deaths from dehydration caused by infection with an enteric pathogen, but it has not changed the morbidity caused by such infections. This Review focuses on the interactions bet...