1,4-bis(triphenylphosphonium)-2-butene dichloride was developed as a new phase transfer catalyst. This quaternized phosphonium salt catalyzed the regioselective ring opening of epoxides by thiocyanate ion to give β-hydroxy thiocyanates in high yields under mild conditions.

Template copolymerization methods have been utilized to prepare porous materials with immobilized cobalt complexes that catalyze the hydrolytic kinetic resolution of epoxides.

The stereospecific and regioselective C(3) alkynylation of trisubstituted epoxides has been achieved with lithium alkynyl trimethylaluminium ate complexes in the presence of BF3 x OEt2.

Merging Jørgensen's and MacMillan's organocatalytic aldehyde chlorinations enables the synthesis of chiral vinylcyclopropanes and (-)-cis-aerangis lactone via terpene-derived 1,2-epoxides.

Lithiated epoxides react stereospecifically with boronic esters to give syn-1,2-diols, a process that can be used iteratively to create triols containing four stereogenic centers.

An efficient coupling reaction of epoxides with CO2 affording cyclic carbonates with the use of 2,2',2''-terpyridine as catalyst under solvent-free conditions has been developed.

The metallophthalocyanine complex Cr(TBPC)OTf works as a highly efficient, recyclable Lewis acid catalyst for the regio- and stereoselective rearrangements of epoxides to aldehydes.

Mechanistic studies have revealed that the isospecific polymerization of epoxides by a discrete salen cobalt(III) catalyst occurs at the surface of the undissolved, crystalline complex.

The 1990 Clean Air Act Amendments list several volatile organic chemicals as hazardous air pollutants, including ethylene oxide, butadiene, styrene, and acrylonitrile. The toxicology of many of these compounds shares several common elements such as carcinogenicity in laboratory animals, genotoxicity of the epoxide intermediates, involvement of cytochrome P450 for metabolic activation (except et...

Four glutathione transferases (EC 2.5.1.18), glutathione transferases A, B, and C and a hitherto unknown form, termed X, were purified to apparent homogeneity from rat liver cytosol. They were investigated for their abilities to inactivate two mutagenic epoxides derived from the polycyclic aromatic hydrocarbon benz(a)anthracene, the K-region epoxide benz(a)anthracene 5,6-oxide and the diol-epox...