Histologic transformation of follicular lymphoma to an aggressive non-Hodgkin lymphoma is a critical biologic event with profound implications on the natural history of this otherwise indolent disease. Recent insights into the genetic and epigenetic basis of transformation have been described, with the recognition of pivotal events governing the initiation and persistence of tumor evolution. Ou...

The 40-yr ECMWF Re-Analysis (ERA-40) data are analyzed to demonstrate that wave forcing at lower latitudes plays a crucial role in driving the tropical upwelling portion of the Brewer–Dobson circulation. It is shown that subtropical wave forcing is correlated with tropical upwelling on both intraseasonal and interannual time scales when transient waves are taken into account, and that tropical ...

[1] The energy input to the upper ocean Ekman layer is assessed for the Southern Ocean by examining the rotary cross spectrum between wind stress and surface velocity for frequencies between 0 and 2 cpd. The wind stress is taken from European Center for Medium-Range Weather Forecasts ERA-40 reanalysis, and drifter measurements from 15 m depth are used to represent surface velocities, with an ad...

We are now in the post-PC era, yet our mobile devices are insecure. We consider the different stake-holders in today’s mobile device ecosystem, and analyze why widely-deployed hardware security primitives on mobile device platforms are inaccessible to application developers and end-users. We systematize existing proposals for leveraging such primitives, and show that they can indeed strengthen ...

A new era of robotics research is being driven by pressing societal problems and creating a transformation in the way that we envision humanrobot interactions. In this chapter, we discuss three application domains that best capture both the promise and the challenges that this transformation has generated: the effort to build robots that support cognitive and social growth, robots that work in ...

Maintain confidentiality, privacy and security research in data mining (PPDM) is one of the biggest trends. Recent advances in data collection, data dissemination and related technologies have inaugurated a new era of research where existing data mining algorithms should be reconsidered from a different point of view, this of privacy preservation. We propose a simple PCA based transformation ap...

To improve responsiveness, oftentimes developers use asynchronous programming. In the post-PC era, asynchronous programming is even more in demand because mobile and wearable devices have limited resources and access the network excessively. One contemporary development task is refactoring long-running, blocking synchronous code (e.g., accessing the web, cloud, database, or file system) into no...