نتایج جستجو برای: esbl

تعداد نتایج: 3894  

2016
Tohru Miyoshi-Akiyama Jatan Bahadur Sherchan Yohei Doi Maki Nagamatsu Jeevan B. Sherchand Sarmila Tandukar Norio Ohmagari Teruo Kirikae Hiroshi Ohara Kayoko Hayakawa

The global spread of extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli (ESBL-E. coli) has largely been driven by the pandemic sequence type 131 (ST131). This study aimed to determine the molecular epidemiology of their spread in two Asian countries with contrasting prevalence. We conducted whole-genome sequencing (WGS) of ESBL-E. coli ST131 strains collected prospectively from Nep...

2016
Mohammad Reza Sharif Babak Soltani Alireza Moravveji Mahzad Erami Nika Soltani

INTRODUCTION Production of extended spectrum beta lactamase (ESBL) is an important mechanism of antimicrobial resistance in Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) isolates. This study was performed to determine the prevalence and risk factors associated with ESBL producing strains of E. coli and K. pneumoniae. METHODS In this cross-sectional study, 250 strains (1...

2014
Acaku Moses Freddie Bwanga Yap Boum Joel Bazira

AIM To determine the prevalence and genotypic characterisation of extended spectrum beta-lactamases produced by gram negative bacilli isolated at Mbarara Regional Referral Hospital (MRRH). SAMPLES Gram negative clinical isolates. STUDY DESIGN Laboratory-based descriptive cross-sectional study. PLACE AND DURATION OF THE STUDY MRRH, June and August 2012. METHODS Gram negative clinical iso...

2017
Valérie O Baede Els M Broens Mirlin P Spaninks Arjen J Timmerman Haitske Graveland Jaap A Wagenaar Birgitta Duim Joost Hordijk

BACKGROUND Close contact between pets and owners provides the opportunity for transmission of antimicrobial resistant organisms like extended-spectrum beta-lactamase (ESBL)/AmpC beta-lactamase (AmpC)-producing Enterobacteriaceae, posing a risk to public health. OBJECTIVES To investigate whether raw feed is a risk factor for household cats to shed ESBL-producing Enterobacteriaceae, a cohort st...

2017
Chung-Hsun Lee Feng-Yuan Chu Chih-Chia Hsieh Ming-Yuan Hong Chih-Hsien Chi Wen-Chien Ko Ching-Chi Lee

The incidence of community-onset bacteremia caused by extended-spectrum-β-lactamase (ESBL) producers is increasing. The adverse effects of ESBL production on patient outcome have been recognized and this antimicrobial resistance has significant implications in the delay of appropriate therapy. However, a simple scoring algorithm that can easily, inexpensively, and accurately be applied to clini...

2016
Ming-Horng Tsai I-Ta Lee Shih-Ming Chu Reyin Lien Hsuan-Rong Huang Ming-Chou Chiang Ren-Huei Fu Jen-Fu Hsu Yhu-Chering Huang

Extended-spectrum β-lactamase (ESBL)-producing Gram-negative bacteremia (GNB) in the neonatal intensive care unit was characterized by comparison with two control groups: a susceptible control group and a general base population group over 2001 to 2012. The influence of ESBL production on mortality was studied in all study subjects and ESBL-GNB isolates were microbiologically characterized. We ...

Journal: :The Journal of the Association of Physicians of India 2011
Neha Gupta T Sohanlal Rajeev Soman Anjali Shetty Camilla Rodrigues

BACKGROUND In India, there is a high prevalence of ESBL producing organisms among intraabdominal isolates and in stool flora of 'normal' individuals. Hence, it may be presumed that unless antimicrobial therapy effective for ESBL flora is used perioperatively for abdominal surgery, the outcome will be adverse. We selected patients surgically treated for appendicitis as a model to explore the rel...

Journal: :Enfermedades infecciosas y microbiologia clinica 2014
Keite da Silva Nogueira Maria Cristina Paganini Andréia Conte Laura Lúcia Cogo Iara Taborda de Messias Reason Márcio José da Silva Libera Maria Dalla-Costa

BACKGROUND Extended-spectrum β-lactamases (ESBLs) are increasingly prevalent in Enterobacter spp., posing a challenge to the treatment of infections caused by this microorganism. The purpose of this retrospective study was to evaluate the prevalence, risk factors, and clinical outcomes of inpatients with bacteremia caused by ESBL and non ESBL-producing Enterobacter spp. in a tertiary hospital o...

2014
LOKESH RAVI

The anti-ESBL activity of 1, 2-benzenedicarboxylic acid, mono (2-ethylhexyl) ester (DMEHE) extracted from marine Streptomyces sp strain VITSJK8 was further confirmed by in silico analysis. A total of 10 ESBL proteins was chosen for this study from the protein data bank (PDB) and were docked with the DMEHE. The resultant atomic contact energy (ACE) was compared with dockings of known antibiotic ...

Journal: :African health sciences 2013
B O Motayo P A Akinduti F A Adeyakinu P O Okerentugba J C Nwanze C C Onoh H C Innocent-Adiele I O Okonko

BACKGROUND The increased reports of ESBL dissemination from various centres in south western, Nigeria and the recent emergence of carbapenem resistant bacteria prompted the conception of this study. OBJECTIVES To demonstrate the relationship between high molecular weight plasmids and the expression of antibiotic multi-resistance including ESBL and carbapenemase. METHODS We investigated 97 i...

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