In the current era, an ever-emerging threat of multidrug-resistant (MDR) pathogens pose serious health challenges to mankind. Researchers are uninterruptedly putting their efforts design and develop alternative, innovative strategies tackle antibiotic resistance displayed by varied pathogens. Among several naturally derived chemically synthesized compounds, quinones have achieved a distinct pos...

In 2009, the Infectious Diseases Society of America (IDSA) set the acronym ESKAPE, which lists the groups of pathogens that pose the highest threat to patients’ safety and to public health [1], one of which is Acinetobacter baumannii [1].Acinetobacter baumannii is a particularly challenging pathogen because it is associated with a high degree of resistance [2], and it is difficult to eliminate ...

Biofilm-related infections account for at least 65% of all human infections, but there are no available antimicrobials that specifically target biofilms. Their elimination by available treatments is inefficient since biofilm cells are between 10- and 1,000-fold more resistant to conventional antibiotics than planktonic cells. Here we describe the synergistic interactions, with different classes...

Clay minerals are naturally occurring layered phyllosilicates which consist of fine particles and possess antimicrobial activity. In a recent article, Behroozian et al. obtained Kisameet clay (KC) from Kisameet, from the central coast of British Columbia, Canada, northwest of Vancouver and assessed its antimicrobial activity versus 16 selected ESKAPE pathogens (Enterococcus faecium, Staphylococ...