BACKGROUND Non cardiac chest pain can be caused by esophageal problems such as gastroesophageal reflux or smooth muscle motor disorders. AIM To perform esophageal manometry in patients with non cardiac chest pain. MATERIAL AND METHODS One hundred patients with chest pain in whom coronary problems were discarded, were studied. A computerized esophageal manometry was performed in all and 24 h...

Esophageal cancer is the eighth most common cancer and causes the sixth highest cancer-related mortality worldwide. The 5-year survival of patients suffering from esophageal cancer in either advanced stage or metastasis is less than 20%. MicroRNAs are small, well conserved, non-coding RNA molecules that either repress translation or promote mRNA degradation based on the degree of complementary ...

The aim of the present study was to explore a disintegrin and metalloproteinase 17 (ADAM17) mRNA and protein expression in esophageal squamous cell carcinoma and its association with clinicopathological factors and prognosis. Through semi‑quantitative reverse transcription polymerase chain reaction, the ADAM17 mRNA expression in 50 cases of esophageal squamous cell carcinoma and corresponding n...

BACKGROUND/AIMS An association between ineffective esophageal motility and gastroesophageal reflux disease is already known, but there are also some conflicting data. We evaluated the association between ineffective esophageal motility and gastroesophageal reflux disease in patients who underwent ambulatory pH monitoring for the evaluation of reflux symptoms at Gazi University, Gastroenterology...

BACKGROUND Asthmatics are known to have esophageal hypomotility. Vagal hypofunction and prolonged intra-esophageal acidification cause esophageal hypomotility. The contribution of gastroesophageal reflux (GER) and vagal function to esophageal motility in asthmatics is unclear. We studied the relationship between esophageal motility, GER and vagal function in a cohort of adult asthmatics. METH...

We examined disintegrin and metalloproteinase 17 (ADAM17) protein expression in esophageal squamous cell carcinoma and its clinical and pathological correlated factors. Western blotting and immunohistochemistry were used to detect ADAM17 protein expression in esophageal squamous cell carcinoma and the corresponding normal esophageal mucosa in 50 cases. ADAM17 protein expression in 50 cases with...

13 ESOPHAGEAL MOTILITY TESTING Occasionally endoscopy and barium esophagogram reports contain information about esophageal motility. Still, esophageal manometry is considered the gold standard in evaluating and quantifying esophageal motility. Esophageal manometry in patients with GERD is recommended to investigate the presence of esophageal motility abnormalities associated with GERD and to lo...

UNLABELLED The mechanism underlying the progression of normal esophageal mucosa to esophageal adenocarcinoma remains elusive. WNT5A is a noncanonical WNT, which mainly functions via the receptor tyrosine kinase-like orphan receptor 2 (ROR2), and has an unclear role in carcinogenesis. In this study, we aimed to determine the role of WNT5A/ROR2 signaling in esophageal adenocarcinoma. Analysis of ...

How to cite: Gharpure V. Esophageal atresia with/without tracheoesophageal fistula. QUESTIONS 1. What clinical and sonographic features should make one suspect esophageal atresia in a pregnancy? 2. What is the quickest method of diagnosing esophageal atresia, with or without tracheo-esophageal fistula (TEF)? 3. What management principles should be followed in a newborn with esophageal atresia ±...