In the MUSE classification of gastroesophageal reflux disease (GERD), esophagitis is assessed by the presence of metaplasia, ulcer, stricture, or erosion, each being graded as absent, mild or severe. Daily reflux symptoms affect about 4 to 7 percent of the population; erosive esophagitis occurs in about 2 percent; the prevalence rate of Barrett's metaplasia is 0.4 percent; and esophageal adenoc...

BACKGROUND In patients with non-cardiac chest pain (NCCP), gastroesophageal reflux disease (GERD) is thought to be the commonest cause. Ambulatory pH monitoring and/or endoscopy are usually performed in order to confirm GERD diagnosis. At present, clinical diagnosis of reflux in patients with NCCP is uncertain.The aim of the study was to determine clinical characteristics that could identify GE...

BACKGROUND AND OBJECTIVE Gastroesophageal reflux disease (GERD) has been linked to a number of extra-esophageal symptoms and disorders, primarily in the respiratory tract. Current animal models of reflux esophagitis are adapted to diseases of the digestive system, rather than to reflux-associated respiratory symptoms. The aim of this study was to evaluate a novel external esophageal perfusion m...

The role of radiologic imaging in evaluating patients with suspected GERD has been clarified in recent years. The barium esophagram is used primarily for detecting the gross morphologic changes of reflux esophagitis and is a reliable screening method for diagnosing the more severe grades of disease. Evaluation of gastroesophageal reflux by barium examination is less certain; the technique is po...

The relationship between hiatal hernias and gastroesophageal reflux disease (GERD) has been greatly debated over the past decades, with the importance of hiatal hernias first being overemphasized and then later being nearly neglected. It is now understood that both the anatomical (hiatal hernia) and the physiological (lower esophageal sphincter) features of the gastroesophageal junction play im...

Gastroesophageal reflux disease (GERD) is caused by abnormal reflux of gastric contents into the esophagus. GERD can be divided into two groups, erosive esophagitis and non-erosive reflux disease (NERD). The aim of this study was to compare the clinical characteristics of patients with erosive esophagitis to those with NERD. All participating patients underwent an upper endoscopy during a volun...

Gastroesophageal reflux disease (GERD) is one of the most common causes health care seeking at primary level in many countries. At an epidemiological level, GERD has been shown to be associated with a number risk factors: obesity, tobacco smoking, alcohol abuse, certain patterns eating behaviour, and use several medications. now regarded as heterogeneous includes different phenotypes (erosive d...

introduction: laryngopharyngeal reflux (lpr) is considered an important cause of voice disorder. we aimed to determine the frequency of lpr in patients with voice disorder and the association between koufman reflux symptom index (rsi), reflux finding score (rfs), gastroesophageal reflux disease (gerd), and proximal acid reflux in these patients. materials and methods: we performed a prospective...

Patients with obstructive sleep apnea (OSA) commonly report gastroesophageal reflux disease (GERD) symptoms, and limited data suggest a relationship between OSA GERD-related complications. To investigate this association, we performed population-based analysis using National Inpatient Sample (NIS) for 7,159,694 patients. After adjusting risk factors, patients had significantly higher incidence ...

OBJECTIVE Gastroesophageal reflux disease (GERD) is a common disease which can cause troublesome symptoms and affect quality of life. In addition to esophageal complications, GERD may also be a risk factor for extra-esophageal complications. Both GERD and coronary artery disease (CAD) can cause chest pain and frequently co-exist. However, the association between GERD and acute myocardial infarc...