PURPOSE The present study was undertaken to examine the relationship between choroidal permeability and scleral glycosaminoglycan synthesis rates during the development of and recovery from form deprivation myopia. METHODS Form deprivation myopia was induced in chicks for 10 days and was followed by a period of unrestricted vision for 0 to 15 days (recovery). Choroidal permeability was quanti...

The effects of home-based HIV counseling and testing on HIV/AIDS stigma among individuals and community leaders in western Kenya: Evidence from a clusterrandomized trial Corinne Low, Cristian Pop-Eleches, Winnie Rono, Evan Plous, Angeli Kirk, Samson Ndege, Markus Goldstein & Harsha Thirumurthy a Department of Economics, Columbia University, NY, USA b School of International and Public Affairs, ...

LENGEROVA (1957) obtained indirect evidence that placental permeability to transplantation antigens could be induced in the rat by delivering 200 r. of X-irradiation to the pregnant uterus on the 15th day of gestation. The young were found subsequently to be immunologically tolerant of grafts of maternal skin. The passage of transplantation antigens into the foetus in sufficient quantity to ind...

Multiple-indicator-dilution experiments were performed in the lungs of 13 anesthetized dogs by simultaneous bolus injection of 111In-labeled neutrophils, 51Cr-labeled red blood cells, and Evans blue-labeled albumin. Concomitant counts of unlabeled neutrophils were similar in pulmonary artery and aortic blood samples, demonstrating a dynamic balance across the lungs in the physiological state. O...

Alessandra Buonanno,* Bala R. Iyer, Evan Ochsner, Yi Pan,1,x and B. S. Sathyaprakash3,k Maryland Center for Fundamental Physics, Department of Physics, University of Maryland, College Park, Maryland 20742, USA Raman Research Institute, Bangalore, 560 080, India School of Physics and Astronomy, Cardiff University, 5, The Parade, Cardiff, United Kingdom, CF24 3YB (Received 6 July 2009; published ...

Unilateral reversible osmotic opening of the blood-brain barrier can be produced in mice. Infusion of 1.8 molal arabinose in water at a rate of 0.64 ml/min for 30 seconds into the internal carotid artery consistently results in ipsilateral brain staining by intravascular Evans blue dye. Osmotic opening is concentration-dependent (threshold, 1.6 molal arabinose) and reversible within 4 hours. No...

Objective. To improve the existing experimental model of croton oil-induced hemorrhoids in rats by using Evans Blue (EB) dye extravasation technique. Further, an herbal formulation (Pilex) was evaluated for its antihemorrhoidal activity in this model. Methods. Two sets of experiments were carried out: first to improve the experimental model and to validate the same using Pilex and second to eva...

Recent studies have shown that up to 90% of viral vectors could disseminate to normal organs following intratumoral infusion. The amount of dissemination might be dependent on the infusion conditions. Therefore, we investigated the effects of infusion rate, volume, and dose on transgene expression in liver and tumor tissues after intratumoral infusion of an adenoviral vector encoding luciferase...

Inducible nitric oxide (NO) synthase (iNOS)-mediated hyperproduction of NO in airways has been reported in asthmatic patients. However, the role of NO in the pathogenesis of asthma has not yet been fully elucidated. The aim of this study was to examine whether the iNOS-derived NO affects airway microvascular leakage, one of the characteristic features of asthmatic airway inflammation. Guinea-pi...

High doses of diatrizoate meglumine-60 were administered intravenously in varying concentrations to determine what effect they might have on the blood-brain barrier. In dogs, doses of 4 ml / kg and above appeared to disrupt parts of the blood-brain barrier, disruption being manifested on computed tomographic scans as enhancement and on corresponding brain sections as Evans blue stains. Disrupti...