نتایج جستجو برای: excisional wound

تعداد نتایج: 72218  

Journal: :Blood 2011
Yuji Okuno Ayako Nakamura-Ishizu Kazuo Kishi Toshio Suda Yoshiaki Kubota

Bone marrow-derived cells (BMDCs) contribute to postnatal vascular growth by differentiating into endothelial cells or secreting angiogenic factors. However, the extent of their endothelial differentiation highly varies according to the angiogenic models used. Wound healing is an intricate process in which the skin repairs itself after injury. As a process also observed in cancer progression, n...

Journal: :Stem cells 2005
Wonhee Suh Koung Li Kim Jeong-Min Kim In-Soon Shin Young-Sam Lee Jae-Young Lee Hyung-Suk Jang Jung-Sun Lee Jonghoe Byun Jin-Ho Choi Eun-Seok Jeon Duk-Kyung Kim

Endothelial progenitor cells (EPCs) act as endothelial precursors that promote new blood vessel formation and increase angiogenesis by secreting growth factors and cytokines in ischemic tissues. These facts prompt the hypothesis that EPC transplantation should accelerate the wound-repair process by facilitating neovascularization and the production of various molecules related to wound healing....

2013
Margrete Berdal Trond Jenssen

Impaired wound healing is a frequent problem in diabetes. Hyperglycemia may be an operative mechanism, but a link between glycemic control and wound healing has never been established. Wounds in db/db mice have been extensively studied. This study was undertaken to see if plasma glucose was a predictor of wound healing. An excisional wound was made (149 db/db mice). Wound closure was studied ve...

Journal: :Agricultural Science Digest – A Research Journal 2023

Background: Teucrium polium a member of Lamiaceae family is widely used plant in Algerian traditional medicine; however, there are few reports on its use as healing agent. The aim this study to investigate the wound property aerial part excisional wounds. Methods: Twenty adult male Wistar rats with an average weight 180 g were study. Post development, 10 received daily treatment ointment and re...

Journal: :Journal of Investigative Dermatology 2022

While human and other mammals are limited in their abilities to regenerate, amphibians, including salamander species such as the axolotl (Ambystoma mexicanum), highly regenerative. Contrary prevailing notion that healing via embryonic-like regeneration necessarily requires a specialized “blastema” tissue, we show axolotls regenerate new skin with anatomically complex secretory glands without bl...

2015
Radwa A. Mehanna Iman Nabil Noha Attia Amany A. Bary Khalid A. Razek Tamer A. E. Ahmed Fatma Elsayed

Bone marrow-derived mesenchymal stem cells (BM-MSCs) represent a modern approach for management of chronic skin injuries. In this work, we describe BM-MSCs application versus their conditioned media (CM) when delivered topically admixed with fibrin glue to enhance the healing of chronic excisional wounds in rats. Fifty-two adult male rats were classified into four groups after induction of larg...

2015
Jason Orr Brant Maria-Cecilia Lopez Henry V. Baker W. Brad Barbazuk Malcolm Maden Paul McNeil

The African spiny mouse (Acomys spp.) can heal full thickness excisional skin wounds in a scar-free manner with regeneration of all dermal components including hair and associated structures. Comparing Acomys scar-free healing from Mus scarring identifies gene expression differences that discriminate these processes. We have performed an extensive comparison of gene expression profiles in respo...

2017
Maryam Mohsenikia Shahrzad Khakpour Zahra Azizian Soheil Ashkani-Esfahani Seyyede Tahereh Razavipour Pooya Toghiani

BACKGROUND Wound healing is a complex process leading to regeneration of damaged skin tissue. Arnebia euchroma (AE) have many effective activities such as anti-inflammatory, antimicrobial, antioxidative, and anti-tumoral effects. The extract of AE has positive effects on burn wounds. This study is designed to investigate the healing effects of AE on excisional wounds in rats. MATERIALS AND ME...

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