Estimation of the modal parameters of mechanical systems or structures is usually achieved by applying the well-known Frequency Response Function (FRF) method to experimental data obtained from free vibration after a shock excitation of the system or forced vibration using a variety of excitation signals. This method is however limited only to linear systems. The problem becomes more complex wh...

A recent experimental study investigating patients with lone atrial fibrillation identified six novel mutations in the KCNA5 gene. The mutants exhibited both gain- and loss-of-function of the atrial specific ultra-rapid delayed rectifier K+ current, IKur. The aim of this study is to elucidate and quantify the functional impact of these KCNA5 mutations on atrial electrical activity. A multi-scal...

the suppression of the regenerative chatter phenomenon in turning process via the variation of the frequency and amplitude of the spindle motor excitation is carried out in this research. a programmable inverter is employed for variable periodic excitation of the spindle motor. a set of turning experiments is designed and performed on a number of conical work pieces both in constant spindle spe...

In this paper, model reference neural network structure is used as a controller for vibration suppression of the Euler–Bernoulli beam under the excitation of moving mass travelling along a vibrating path. The non-dimensional equation of motion the beam acted upon by a moving mass is achieved.  A Dirac-delta function is used to describe the position of the moving mass along the beam and its iner...

In the mouse model of Fragile X syndrome, the Fmr1 knock-out, local excitation of layer 4 fast-spiking (FS) inhibitory neurons is robustly decreased by 50%, but the mechanisms mediating this change are unknown. Here, we performed recordings in acutely prepared slices obtained from Fmr1 "mosaic" mice, where Fmr1 is deleted in about half of all neurons, and we found that loss of presynaptic, but ...