Erythroderma is a rare potentially deadly exfoliative dermatitis characterized by diffuse cutaneous erythema which may be associated with multi-organ dysfunction. Therefore, it is imperative to recognize and treat it promptly. Erythrodermic psoriasis is the most common form of erythroderma. Management of this condition is largely based on aggressive supportive care and the use of anti-inflammat...

1. Storer JS, DeLeon I, Millikan LE, Laseter JL, Grifting C. Human absorption of crude coal tar products. Arch Dermatol 1984; 120: 874 ± 877. 2. Hansen AM, Poulsen OM, Menne T. Longitudinal study of excretion of metabolites of polycyclic aromatic hydrocarbons in urine from two psoriatic patients. Acta Derm Venereol 1993; 73: 188 ± 190. 3. Mackenzie KM, Angevine DM. Infertility in mice exposed ...

We sought a possible correlation between the clinical manifestations of staphylococcal scalded-skin syndrome (SSSS) and the serotype of exfoliative toxins (ET) by PCR screening of the eta and etb genes in Staphylococcus aureus strains isolated from 103 patients with generalized SSSS and 95 patients with bullous impetigo. The eta gene and the etb gene were detected in, respectively, 31 (30%) and...

Erythroderma (exfoliative dermatitis) associates with important metabolic changes that include an enhancement in energy expenditure. The key components to total expenditure (TEE) basal rate (~68% of TEE), physical activity (~22% TEE) and thermic effect food (~10% TEE). In the erythrodermic state, there are likely multiple contributors increase such as 'caloric drain' resulting from increased ev...

Conflicts of interest: The authors have declared no conflicts. hands, legs below knee level, and the area between the shoulder blades (Fig. 1). The patient had no history of dermatological disease and no prior or present exposure to sunlight, infection, or drugs. Biochemical screening was normal, skin cultures were negative, and a biopsy from lesional skin showed changes compatible with dermati...

Exfoliative cheilitis is an inflammatory condition that can significantly impair quality of life. This the first reported case interleukin-23 inhibitor, tildrakizumab, for treatment a chronic, refractory exfoliative cheilitis.

OBJECTIVE To investigate the occurrence and clinical characteristics of dapsone-related adverse drug reactions (ADRs) among leprosy patients who underwent multidrug therapy (MDT) from 2010 to 2013 in the western region of Nepal. METHODS A retrospective review was carried out in the rehabilitation center. Data were collected from the record files of the hospital. RESULTS From 2010 to 2013, t...

INTRODUCTION Erythroderma is defined as generalized redness and scaling affecting more than 90% of the skin surface and often accompanied by systemic complications such as hypothermia, dehydration, and electrolyte imbalance. Treatment is targeted at the underlying cause, and preexisting dermatoses are identified in 65% of patients. Psoriasis is the most common underlying disease in erythrodermi...