Sharafkhaneh, Amir, Todd M. Officer, Sheila GoodnightWhite, Joseph R. Rodarte, and Aladin M. Boriek. Novel method for measuring effects of gas compression on expiratory flow. Am J Physiol Regul Integr Comp Physiol 287: R479–R484, 2004. First published April 29, 2004; 10.1152/ajpregu.00573.2003.—During forced vital capacity maneuvers in subjects with expiratory flow limitation, lung volume decre...

   Cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. However, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma.    The purpose of this study was to determine the extent of change...

   Cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. However, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma.    The purpose of this study was to determine the extent of change...

Lung function testing in children is an important part of assessment, diagnosis and monitoring of children with lung disease. Regular testing can also be used to evaluate lung growth, review the effects of treatment and assess the risks and benefits of specific clinical interventions. Such tests can also be useful in the pre-operative assessment of high risk patients undergoing surgical procedu...

Measurements of relaxed expiratory volume in one second (REV1.0) and forced inspiratory volume in one second (FIV1.0) were made on 50 subjects on two occasions to know the variability of these procedures in the individual subject. The mean coefficients of variation for REV1.0 and FIV1.0 were 6740' and 892%, respectively. The 95% confidence limit of difference between highest readings obtained o...