نتایج جستجو برای: extranodal nk

تعداد نتایج: 23657  

2017
Eric Tse Yok-Lam Kwong

Extranodal natural killer (NK)/T-cell lymphoma is an aggressive malignancy of putative NK-cell origin, with a minority deriving from the T-cell lineage. Pathologically, the malignancy occurs in two forms, extranodal NK/T-cell lymphoma, nasal type; and aggressive NK-cell leukaemia. Lymphoma occur most commonly (80%) in the nose and upper aerodigestive tract, less commonly (20%) in non-nasal area...

2013
Danny K. C. Wong Angus Shao Michael Davison

Extranodal natural killer (NK)/T-cell lymphomas are rare tumors that account for 1.5% of all non-Hodgkin-type lymphomas in the United States and almost 7–10% of all non-Hodgkin’s lymphomas in Asia and South America. The nasal type commonly presents with facial cellulitis, nasal obstruction or proptosis. Occasionally, local extension from the nasal cavity causes destruction of the hard palate, p...

2013
Tsung-Hsien Lin Yen-Chuan Hsieh Sheng-Tsung Chang Shih-Sung Chuang

The relative frequency of lymphoma types varies in different geographic region. Human Tcell lymphotropic virus type I (HTLV-I) infection is endemic in south-western Japan which leads to a high frequency of adult T-cell leukemia/lymphoma (ATLL). As compared to the West, East Asian countries have higher relative frequencies of Tand natural killer (NK)-cell lymphomas, which account for about 15-20...

Journal: :Blood 2012
Hiroshi Kimura Yoshinori Ito Shinji Kawabe Kensei Gotoh Yoshiyuki Takahashi Seiji Kojima Tomoki Naoe Shinichi Esaki Atsushi Kikuta Akihisa Sawada Keisei Kawa Koichi Ohshima Shigeo Nakamura

EBV-associated T/NK-cell lymphoproliferative disease (T/NK-LPD) is defined as a systemic illness characterized by clonal proliferation of EBV-infected T or NK cells. We prospectively enrolled 108 nonimmunocompromised patients with this disease (50 men and 58 women; median onset age, 8 years; age range, 1-50 years) evidenced by expansion of EBV(+) T/NK cells in the peripheral blood; these were o...

2006
Ritsuro Suzuki

Malignant hematolymphoid disorders arising from NK cells have become widely recognized over the past decade. The two forms of NK-cell malignancy, aggressive NK-cell leukemia (ANKL) and extranodal NK-cell lymphoma of nasal type (ENKL) are both characterized by the proliferation of tumor cells with an NK-cell like immunophenotype. ANKL usually presents with bone marrow tumor cells accompanied by ...

Journal: :European Annals of Otorhinolaryngology, Head and Neck Diseases 2012

2017
Erika Reategui Schwarz Katerina G. Oikonomou Megan Reynolds Juliette Kim Rajeev L. Balmiki Stephanie A. Sterling

Extranodal natural killer T-cell lymphoma, nasal type (ENKL), formerly called lethal midline granuloma or angiocentric T-cell lymphoma, is a predominantly extranodal non-Hodgkin lymphoma characterized by vascular damage, necrosis, and an association with Epstein-Barr virus. In the United States, it is more frequently seen in Asian, Asian Pacific Islander, and Hispanic descent populations and is...

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