A Pareto Local Search (PLS) algorithm was developed and applied to the screw configuration of co-rotating twin-screw extruders. This problem can be seen as a sequencing problem where a set of different screw elements are to be sequentially positioned along the screw in order to maximize the extruder performance. The results obtained were compared with previous results obtained with a Multi-Obje...

During pandemics and global crises, drug shortages become critical as a result of increased demand, in personnel lockdown restrictions that disrupt the supply chain. The pharmaceutical industry is therefore moving towards continuous manufacturing instead conventional batch involving numerous steps, normally occur at different sites. In order to validate use large-scale industrial processes, fea...

The article highlights one of the ways to improve design extruder body in order increase reliability and, at same time, quality extrusion. object research is a single-worm extruder. One most problematic areas body. main disadvantage wear surfaces due corrosion or abrasion and requires regular replacement. This abrasive properties polymers accordingly, friction polymer material against worm, esp...