Wnt/MAPK signaling is a common variant of Wnt signaling in C. elegans and has been implicated in vertebrates. The sys-1 gene works with Wnt/MAPK signaling to control cell fates during C. elegans development. We report that the SYS-1 amino acid sequence is novel but that SYS-1 functions as beta-catenin: SYS-1 rescues a bar-1/beta-catenin null mutant, binds the POP-1/TCF beta-catenin binding doma...

Sys-Rem (Tamuz, Mazeh & Zucker 2005) is a detrending algorithm designed to remove systematic effects in a large set of lightcurves obtained by a photometric survey. The algorithm works without any prior knowledge of the effects, as long as they appear in many stars of the sample. This paper presents the basic principles of Sys-Rem and discusses a parameterization used to determine the number of...

Introduction The Triple-S project (Syndromic Surveillance Systems in Europe, www.syndromicsurveillance.eu), co-financed by the European Commission and involving twenty four organizations from fourteen countries was launched in September 2010 with the following objectives 1) performing an inventory of existing or planned SyS systems in Europe both in animal and public health, 2) building a netwo...

The Internet consists of a variety of interconnected heterogeneous networks managed by independent providers. At the edges between two networks resources are allocated. In this paper, we present a framework and taxonomy for problems at these edges like admission control and provider selection; we call them multi-period resource allocation problems at system edges (MPRASE). We look at several pr...

Coronary blood flow (CBF) is reduced and transiently reversed during systole via cardiac contraction. Cardiac contractility, coronary tone, and arterial pressure each influence systolic CBF (CBF(SYS)), particularly by modulating the retrograde component of CBF(SYS). The effect of concurrent changes in these factors on CBF(SYS) during dynamic exercise has not been examined. Using chronically ins...

Sistema de Apoio à Decisão para a especialidade de Oftalmologia baseado em técnicas de Workflow e Data Mining aplicadas em dados obtidos em ambiente clínico – Algoritmo de Registo de Imagem and the suggestions, critics and support that they gave me. I also want to thank the management board of Blueworks for the opportunity given. Most important of all, I want to thank my parents, brother, famil...

Objective: To determine the impact of Lean Sigma (LS) on waiting time of patients at different stations of outpatient department (OPD), pre-surgical area and operation room (OR). Methods: In this prospective quality study Define, Measure, Analyse, Improve and Control (DMAIC) model of lean sigma was used for improvement. Lead time of patients during measure phase of DMAIC was assessed using time...

and Applied Analysis 3 13.6 13.605 13.61 13.615 13.62 13.625 13.63 −8.1 −8.08 −8.06 −8.04 −8.02 −8 −10.46 −10.455 −10.45 −10.445 −10.44 sys 1 sys 2 sy s 3

C. elegans embryos exhibit an invariant lineage comprised primarily of a stepwise binary diversification of anterior-posterior (A-P) blastomere identities. This binary cell fate specification requires input from both the Wnt and MAP kinase signaling pathways. The nuclear level of the TCF protein POP-1 is lowered in all posterior cells. We show here that the beta-catenin SYS-1 also exhibits reit...

"This study aims to provide evidence support policymaking by assessing health system perfor mance in the province of Ontario, Canada, and its major cities (Toronto, Mississauga, Oakville, Brampton). It reports on performance care organizations local systems over years 2012-2018. The indicators ana lyzed are grouped into two categories: status quality service (Ontario Ministry Health). analysis ...