Family and Gang as Agents of Socialization The family, conceived primarily as a child-rearing agency, and the gang, defined in some detail in the last chapter, were both prevalent forms of associational units in Midcity. It is important to repeat at this point that the term “family” as used in the present work refers to that kinship-based associational unit which bears primary responsibility fo...

frequent interaction among family members, may lead to conflict or problems. therefore, designing intervention programs for promote interpersonal skills among family members seemed to be necessary. one of these programs is problem solving strategies teaching.  this study aime to investigate the effects of teaching problem solving on parenting style and family problem solving. the sample is cons...

Based on gene sequence homologies, a p53 (TP53) gene family become apparent with the addition of the most recently identified p63 (TP73L; formerly TP63) and p73 (TP73) genes to the already known p53. The p53 gene encodes for a unique protein eliciting well-known tumor suppressor gene (TSG) properties that mediate cellular response to DNA damage, e.g., cell cycle arrest or apoptosis. In contrast...

Interleukin-17A (IL-17A) is the signature cytokine of the recently identified T helper 17 (Th17) cell subset. IL-17 has six family members (IL-17A to IL-17F). Although IL-17A and IL-17F share the highest amino acid sequence homology, they perform distinct functions; IL-17A is involved in the development of autoimmunity, inflammation, and tumors, and also plays important roles in the host defens...

We are describing briefly another family with cardiomyopathy, where a woman and three of her four children were affected. Some of them have been under observation for twelve years and have been examined by the three authors at different periods. The mother had been suspected for many years of having some form of congenital heart disease because of a murmur. She and her three affected children w...

Recent studies show that small trans-membrane proteins of approximately 22-24 kDa (the p24 family), which are grouped into 4 sub-families by sequence homology (p23, p24, p25 and p26), are involved in the early secretory pathway. In this study, we have investigated the mutual requirements of ectopically expressed members of the p24 family for targeting to their proper cellular destination. We fi...

Caveolae are membrane organelles that play roles in glucose and lipid metabolism and in vascular function. Formation of caveolae requires caveolins and cavins. The make-up of caveolae and their density is considered to reflect cell-specific transcriptional control mechanisms for caveolins and cavins, but knowledge regarding regulation of caveolae genes is incomplete. Myocardin (MYOCD) and its r...

1. Use of family members as donors or surrogates is generally ethically acceptable. 2. Brothers may donate sperm to brothers and sisters may donate eggs to sisters. 3. Intergenerational gamete donation and surrogacy are especially challenging. 4. Consanguineous gamete donations from first-degree relatives are unacceptable. 5. Counseling is encouraged for all parties including partners of donors...

*Limb-sparing surgeries may be associated with significant injury to the soft-tissues, compromised lymph-drainage, and lymphedema. The current study summarizes our experience with decongestive-lymphatic-therapy (DLT) in those patients. *Between 1997 and 2001, 26 patients were referred to the DLTservice. There were 15 females and 11 males (age 19–73 years) and diagnosed with 20 soft-tissue and 6...

VEGF, Hedgehog, FGF, Notch, and WNT signaling pathways network together for vascular remodeling during embryogenesis, tissue regeneration, and carcinogenesis. VEGFA (VEGF), VEGFB, VEGFC, VEGFD (FIGF) and PGF (PlGF) are VEGF family ligands for receptor tyrosine kinases, including VEGFR1 (FLT1), VEGFR2 (KDR) and VEGFR3 (FLT4). Bevacizumab (Avastin), Sunitinib (Sutent) and Sorafenib (Nexavar) are ...