In an attempt to explain how and why some individuals with musculoskeletal pain develop a chronic pain syndrome, Lethem et al. (Lethem J, Slade PD, Troup JDG, Bentley G. Outline of a fear-avoidance model of exaggerated pain perceptions. Behav Res Ther 1983;21:401±408) introduced a so-called `fear-avoidance' model. The central concept of their model is fear of pain. `Confrontation' and `avoidanc...

This cross-sectional questionnaire study investigated the role of pain (pain severity, radiating pain), work characteristics (physical workload, job stressors, job satisfaction), negative affect and pain-related fear in accounting for low back pain (LBP) and sick leave (SL) in 1294 employees from 10 companies in Belgium and the Netherlands. An increased risk for short-term LBP (1-30 days during...

objectives: most definitions equate quality of life with motor function. the aim of this study is to examine the association between gross motor function and quality of life for children with cerebral palsy. methods: in this analytical cross–sectional study, 60 children with cerebral palsy aged 4-12 were selected through convenience sampling based on inclusion criteria from occupational therapy...

The visual cortex is sensitive to emotional stimuli. This sensitivity is typically assumed to arise when amygdala modulates visual cortex via backwards connections. Using human fMRI, we compared dynamic causal connectivity models of sensitivity with fearful faces. This model comparison tested whether amygdala modulates distinct cortical areas, depending on dynamic or static face presentation. T...

For the last two or three decades new and alternative religions have been at the center of heated controversy in the United States as various advocates have debated the desirability of curbing the operations of leaders and organizations that, many believe, have abused their followers and constitute a real threat to society. This controversy has spread to the scholarly community that studies thi...

Sleep, and particularly rapid eye movement sleep (REM), has been implicated in the modulation of neural activity following fear conditioning and extinction in both human and animal studies. It has long been presumed that such effects play a role in the formation and persistence of posttraumatic stress disorder, of which sleep impairments are a core feature. However, to date, few studies have th...

objective: social phobia is considered as one of the most common anxiety disorders. the researchers have been looking for the basic mechanism behind it, since determining these factors can be influential in prevention and treatment. in recent years, some of the most important personality and cognitive correlates of social phobia including neuroticism, fear of negative evaluation, anxiety sensit...