Objective: To evaluate spirometric patterns of respiratory disorders and their relationship with functional severity and maximal expiratory flows at low lung volumes in patients with cystic fibrosis (CF). Methods: A retrospective cross-sectional study including adolescents and adults with CF. All of the patients were submitted to spirometry. Patients were classified as having preserved respirat...

OBJECTIVE To determine whether birth weight and gestational age are associated with respiratory illness and lung function in children aged 5-11 years. DESIGN Cross sectional analysis of parent reported birth weight, gestational age, and respiratory symptoms; parental smoking and social conditions; forced vital capacity (FVC), forced expiratory volume in one second (FEV1), forced expiratory ra...

BACKGROUNDS/OBJECTIVES Evidence on the association between physical activity and lung function in children is sparse. The aim of this study was to evaluate children's lung function growth in relation to their physical activity level in Chinese children. METHODS A total of 1713 school children aged 9.89±0.86 years who were asthma-free at baseline were followed-up for 18 months from 2006 to 200...

TIMOTHY D. MICKLEBOROUGH, LOREN CORDAIN, ROBERT W. GOTSHALL, and ALAN TUCKER. A Low Sodium Diet Improves Indices Of Pulmonary Function In Exercise-Induced Asthma. JEPonline, 3(2):46-54, 2000. The purpose of this study was to determine if manipulation of dietary sodium could influence the severity of exercise-induced asthma (EIA). Fifteen clinicallydiagnosed EIA subjects participated in a double...

BACKGROUND This trial aimed to evaluate the efficacy and safety of roflumilast for treating Chinese patients with chronic obstructive pulmonary disease (COPD). METHODS A total of 120 patients with COPD were recruited and were randomly divided into 2 groups (an intervention group and a placebo group) at a 1:1 ratio. Patients received either roflumilast or placebo 500 μg once daily for a total ...

Because aspirin (ASA) is often reported to have an adverse effect on pulmonary function in children with chronic asthma, acetaminophen is commonly used as an ASA substitute in these children. To study acetaminophen effects on pulmonary functions, double-blind, oral challenges of ASA (600 mg), acetaminophen (600 mg), or lactose were administered on separate days to 25 chronic asthmatics, ten boy...

BACKGROUND Although hypothyroidism has an insidious onset and relatively asymptomatic, exertional dyspnea and fatigue can be the presenting complaints. OBJECTIVES The aim is to assess functional lung impairment in hypothyroid patients both at rest and during exercise. METHODS A case-control study was carried out on 42 patients with newly diagnosed hypothyroidism and 12 control subjects. Hyp...

In order to assess the role of genetic factors and environmental influences in bronchial responsiveness, we studied the airway response to an inhaled bronchodilator in 66 nonasthmatic parents (age, 30.9 +/- 5.9 years) of infants with bronchiolitis (group 1). It was a placebo-controlled double-blind study. A control group (group 2) of healthy parents of infants who did not have bronchiolitis als...

1Faculty of Pharmacy, Lebanese University, Beirut, Lebanon (Correspondence to P. Salameh: [email protected]). 2Pulmonology Service, Saint George Hospital, Beirut, Lebanon. 3Faculty of Public Health, Institute of Public Health, Epidemiology and Development (ISPED), Victor Segalen Bordeaux 2 University, Bordeaux, France. Received: 05/06/04; accepted: 25/02/04 ABSTRACT We compared the respi...

BACKGROUND Asthma and obesity are important and growing health issues worldwide. Obesity is considered a risk factor for asthma, due to the induction of changes in airway mechanics and altered airway inflammation. METHODS We cross-sectionally investigated the effect of increased weight on pulmonary function in a large population sample of healthy children, aged 10-17 yrs living in Palermo, It...