This four-document series was created to facilitate improved education and communication for fertility preservation in adolescent and young adult Canadians with a new diagnosis of cancer. The present review outlines gonadal protection options and fertility-sparing strategies for the young cancer patient. Cryopreservation and later use of gamete and gonadal tissue will be addressed in a subseque...

OBJECTIVE To compare fertility-sparing therapies including oral progestogens, hysteroscopic resection (HR), and the levonorgestrel- releasing intrauterine system (LNG-IUS) in achieving disease regression, recurrence and live birth rate in well differentiate early-stage endometrial carcinoma (eEC) and complex atypical hyperplasia(CAH). STUDY DESIGN This was a meta-analysis of previous studies ...

Here we report the outcomes of 26 patients who relapsed following conservative surgical treatment of stage I serous borderline ovarian tumours treated initially with fertility-sparing surgery. All recurrences were diagnosed by systematic ultrasonography during follow-up. Eleven patients relapsed at least twice after such management. Twenty-one pregnancies were observed in 13 patients. Eleven of...

As a result of the trend toward late childbearing, fertility preservation has become a major issue in young women with gynaecological cancer. Fertility-sparing treatments have been successfully attempted in selected cases of cervical, endometrial and ovarian cancer, and gynaecologists should be familiar with fertility-preserving options in women with gynaecological malignancies. Options to pres...

Although paratubal cysts are well-characterized incidental findings, paratubal serous borderline tumors are very rare, with only one case report in the literature. We describe here a 27-year-old, nulliparous, married woman with a paratubal serous borderline tumor. The patient presented with a huge pelvic mass accompanied by flank pain and underwent paratubal cystectomy and fertility-sparing sur...

Clinical and laboratory reports suggest that ovarian tumors of low malignant potential (LMP) represent a "grab bag" of tumors, with different etiologies, molecular biologies, and prognoses. As a result, data on incidence and prognosis may be quite unreliable. Diagnosis is best made on permanent section. Half of women under age 40 undergo conservative, fertility-sparing surgery when diagnosed wi...

The disadvantages of the reviewed studies dealing with fertility-sparing conservative surgery in EOC reported during the last 20 years are inherent in their retrospective nature. Many of the studies include a limited number of patients. The follow-up periods in these studies vary greatly and in some it is not indicated at all. Outcome is often given as the number of patients with recurrence or ...

The study included 26 patients with FIGO stage Ia1–Ib1 cervical cancer who underwent fertility-sparing surgery (transabdominaltrachelectomy). To visualize sentinel lymph nodes, lymphoscintigraphy with injection of 99mTclabelled nanocolloid was performed the day before surgery. Intraoperative identification of sentinel lymph nodes using hand-held gamma probe was carried out to determine the radi...

Borderline ovarian tumours generally affect women of reproductive age. The positive prognosis is related to the fact that over 80% of cases are diagnosed at an early stage of the disease. Although radical surgery is the standard of care for this disease, fertility-sparing surgery can be performed in selected cases. Since it was first described in 1929, the knowledge of the molecular and histolo...

1. Treatment of CIN 2. Invasive Carcinoma of the Cervix 1. Clinical presentation 2. Staging 3. Histology 4. Management 1. Stage 1A 2. Stage IB – 2A 3. Stage 2B – 4A 4. Stage 4B 5. Complications 1. Radical Hysterectomy 2. Radiotherapy 6. Minimal Access Surgery 1. Laparoscopic Vaginal Radical Hysterectomy (LVRH) 7. Fertility Sparing Surgery 8. Special Situations 1. Recurrent Cervical Cancer 2. In...